The role of sheep’s milk bioactive substances in the prevention
of metabolic and viral diseases

Z. Flis; J. Szczecina; E. Molik

doi:10.22358/jafs/151020/2022

3/2022 vol. 31

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The role of sheep’s milk bioactive substances in the prevention of metabolic and viral diseases

Z. Flis ¹

J. Szczecina ¹

E. Molik ¹

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University of Agriculture in Krakow, Faculty of Animal Science, Department of Animal Nutrition and Biotechnology, and Fisheries, 30-059 Krakow, Poland

Publication date: 2022-07-05

Corresponding author

E. Molik

University of Agriculture in Krakow, A. Mickiewicz 24/28 Av., 30-059 Krakow, Poland

J. Anim. Feed Sci. 2022;31(3):211-216

DOI: https://doi.org/10.22358/jafs/151020/2022

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1447_Flis et al_abstract_china.pdf

References (31) Citations (3)

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ABSTRACT

Sheep’s milk exerts a number of biological effects that influence metabolic reactions and disease resistance. Sheep’s milk contains the highest level of casein, whey protein and conjugated linoleic acid isomers (CLA), which stimulate the immune system, and have “anti-obesity”, “antidiabetic” and “anticancer” properties. Sheep’s milk is an excellent source of protein and group B vitamins, which ensure the proper functioning of the nervous system. Proline-rich polypeptide partially reverses neurodegenerative changes and has immunoregulatory and pro-cognitive properties. CLA isomers also reduce oxidative stress and mitochondrial dysfunction in the brain, which may be important in neurodegenerative diseases such as Alzheimer’s disease. Sheep’s milk shows the highest inhibitory activity of angiotensin converting enzyme, which is crucial in preventing SARS-CoV-2 infection. Systemic inflammation is a common factor in atherosclerosis and COVID-19. Polar lipids present in sheep’s milk lower inflammatory biomarkers and reduce the development of atherosclerosis. Therefore, dairy products can be used to help prevent COVID-19 disease. Sheep’s milk and its products containing bioactive substances may be promising ingredients for the production of health-promoting functional foods.

CONFLICT OF INTEREST

The Authors declare that there is no conflict of interest.

METADATA IN OTHER LANGUAGES:

Chinese

羊奶生物活性物质在预防代谢性和病毒性疾病中的作用

关键词：生物活性成分；COVID-19；牛奶；绵羊

摘要: 羊奶具有多种生物效应，影响新陈代谢反应和抗病能力。羊奶含有最高水平的酪蛋白、乳清蛋白和共轭亚油酸异构体羊奶具有多种生物效应，影响新陈代谢反应和抗病能力。羊奶含有最高水平的酪蛋白、乳清蛋白和共轭亚油酸异构体（Conjugated linoleic acid isomers，CLA），这些物质可以刺激免疫系统，并具有抗肥胖、抗糖尿病和抗癌的特性。羊奶是蛋白质和B族维生素最好的来源，它们可确保神经系统的正常功能。富含脯氨酸的多肽（Proline-rich polypeptide，PRP）可部分逆转神经退行性改变，并具有免疫调节和促进认知的特性。CLA异构体还可以减少大脑中的氧化应激和线粒体功能障碍，对预防阿尔茨海默病等神经退行性疾病很重要。羊奶具有最高的血管紧张素转换酶抑制活性，这对预防SARS-CoV-2感染至关重要。全身炎症是导致动脉粥样硬化和COVID-19的共同因素。羊奶中存在的极性脂可降低炎症生物标志物，减少动脉粥样硬化的发展。因此，乳制品可以用来帮助预防COVID-19。羊奶及其含有生物活性物质的产品可能是生产保健功能食品配料的主要发展趋势。

REFERENCES (31)

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