SHORT COMMUNICATION
Growth performance and toxic response of broilers fed diets containing fermented or unfermented cottonseed meal
J.L. Xiong 1,   Z.J. Wang 1,   L.H. Miao 1,   F.T. Meng 1,   L.Y. Wu 1  
 
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Wuhan Polytechnic University, Hubei Key Laboratory of Animal Nutrition and Feed Science, Hubei 430023, Wuhan, China
CORRESPONDING AUTHOR
L.Y. Wu   

Wuhan Polytechnic University, Hubei Key Laboratory of Animal Nutrition and Feed Science, Hubei 430023, Wuhan, China
Publication date: 2016-12-13
 
J. Anim. Feed Sci. 2016;25(4):348–353
 
KEYWORDS
ABSTRACT
The aim of the study was to determine the effects of solid-state fermentation of cottonseed meal (FCSM) with Candida utilis on broiler growth performance and toxicity in comparison to unfermented cottonseed meal (CSM) or soyabean meal (SBM, control). In total 150 one-day-old male Cobb 400 broilers were randomly assigned to 3 dietary treatments with 5 replications of 10 birds each. Animals were fed control diet with SBM, diet with CSM : SBM (1:1) and diet with FCSM : SBM (1:1) until 21 day of life. Fermentation decreased free gossypol content in CSM from 583.40 to 191.70 mg · kg−1, and degraded total gossypol from 5830.19 to 3882.91 mg · kg−1 CSM. In comparison to the control diet, FCSM : SBM (1:1) diet did not affect (P > 0.05) the average daily growth and feed conversion ratio, while CSM : SBM (1:1) diet decreased (P < 0.05) these parameters. However, FCSM : SBM (1:1) diet, similarly to CSM : SBM (1:1) diet, increased (P < 0.05) the relative weight of liver and the serum activity of alanine aminotransferase, and decreased (P < 0.05) the relative weight of thymus in comparison to the control diet. In conclusion, residual gossypol or/and degradation products of gossypol in FCSM may still be hepatotoxic and immunotoxic for broilers when SBM is half-replaced by FCSM in diet (155 g · kg−1), although the contents of free gossypol and total gossypol have been markedly reduced and no adverse effect on growth performance was observed.
 
REFERENCES (16)
1.
Blackwelder J.T., Hopkins B.A., Diaz D.E., Whitlow L.W., Brownie C., 1998. Milk production and plasma gossypol of cows fed cottonseed and oilseed meals with or without rumen-undegradable protein. J. Dairy Sci. 81, 2934–2941, https://doi.org/10.3168/jds.s0...
 
2.
Blevins S., Siegel P.B., Blodgett D.J., Ehrich M., Saunders G.K., Lewis R.M., 2010. Effects of silymarin on gossypol toxicosis in divergent lines of chickens. Poultry Sci. 89, 1878–1886, https://doi.org/10.3382/ps.201...
 
3.
Braga A.P., Maciel M.V., Guerra D.G.F., Maia I.S.A.S., Oloris S.C.S., Soto-Blanco B., 2012. Extruded-expelled cottonseed meal decreases lymphocyte counts in male sheep. Rev. Med. Vet. 163, 147–152
 
4.
Chen K.-L., Kho W.-L., You S.-H., Yeh R.-H., Tang S.-W., Hsieh C.-W., 2009. Effects of Bacillus subtilis var. natto and Saccharomyces cerevisiae mixed fermented feed on the enhanced growth performance of broilers. Poultry Sci. 88, 309–315, https://doi.org/10.3382/ps.200...
 
5.
Deng S., Pawlak A., Poźniak B., Suszko A., Szczypka M., Yuan H., Obmińska-Mrukowicz B., 2012. Effects of gossypol acetic acid on cellular and humoral immune response in non-immunized and SRBC-immunized mice. Cent. Eur. J. Immunol. 37, 11–19
 
6.
Fombad R.B., Bryant M.J., 2004. An evaluation of the use of cottonseed cake in the diet of growing pigs. Trop. Anim. Health Prod. 36, 295–305, https://doi.org/10.1023/B:TROP...
 
7.
Gadelha I.C.N., Fonseca N.B.S., Oloris S.C.S., Melo M.M., Soto-Blanco B., 2014. Gossypol toxicity from cottonseed products. Sci. World J. 2014, 231635, https://doi.org/10.1155/2014/2...
 
8.
Gamboa D.A., Calhoun M.C., Kuhlmann S.W., Haq A.U., Bailey C.A., 2001. Use of expander cottonseed meal in broiler diets formulated on a digestible amino acid basis. Poultry Sci. 80, 789–794, https://doi.org/10.1093/ps/80....
 
9.
Henry M.H., Pesti G.M., Brown T.P., 2001. Pathology and histopathology of gossypol toxicity in broiler chicks. Avian Dis. 45, 598–604, https://doi.org/10.2307/159290...
 
10.
Mena H., Santos J.E.P., Huber J.T., Tarazon M., Calhoun M.C., 2004. The effects of varying gossypol intake from whole cottonseed and cottonseed meal on lactation and blood parameters in lactating dairy cows. J. Dairy Sci. 87, 2506–2518, https://doi.org/10.3168/jds.S0...
 
11.
NRC, 1994. Nutrient Requirements of Poultry. 9th revised Edition. National Academy Press. Washington DC (USA), https://doi.org/10.17226/2114
 
12.
Rincon R., Smith F.H., Clawson A.J., 1978. Detoxification of gossypol in raw cottonseed and the use of raw cottonseed meats as a replacement for soybean meal in diets for growing-finishing pigs. J. Anim. Sci. 47, 865–873, https://doi.org/10.2527/jas197...
 
13.
Sterling K.G., Costa E.F., Henry M.H., Pesti G.M., Bakalli R.I., 2002. Responses of broiler chickens to cottonseed- and soybean meal-based diets at several protein levels. Poultry Sci. 81, 217–226, https://doi.org/10.1093/ps/81....
 
14.
Tang J.W., Sun H., Yao X.H., Wu Y.F., Wang X., Feng J., 2012. Effects of replacement of soybean meal by fermented cottonseed meal on growth performance, serum biochemical parameters and immune function of yellow-feathered broilers. Asian Austral. J. Anim. Sci. 25, 393–400, https://doi.org/10.5713/ajas.2...
 
15.
Willard S.T., Neuendorff D.A., Lewis A.W., Randel R.D., 1995. Effects of free gossypol in the diet of pregnant and postpartum Brahman cows on calf development and cow performance. J. Anim. Sci. 73, 496-507, https://doi.org/10.2527/1995.7...
 
16.
Zhou H.-l., Mei X.-c., Miao L.-h., 2014. Analysis of the cultural characteristics and the effect of fermentation of yeast degrading gossypol (in Chinese). J. Wuhan Polytechnic Univ. 33, 14–16.
 
 
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ISSN:1230-1388