This study aims to investigate the effect of supplementing dietary cinnamon oil (CO) into broiler chicken diets on growth performance, carcass traits, haemato-biochemical parameters, immune function, antioxidant status, and caecal microbial count. Three hundred one-day old broilers were distributed randomly, with 5 replications, into 5 groups (12 birds per replicate). Dietary treatments comprised the basal diet (control group), and the basal diet supplemented by either 10 mg/kg avilamycin or 500, 1000 and 1500 mg/kg of CO. Results indicated that birds from CO-treated groups had higher body weight, weight gain and feed conversion ratio than the control group. Also, birds from CO supplemented groups had lower total cholesterol, triglycerides, lowdensity lipoproteins than those from the control group; the lowest values were recorded in the group treated with 500 mg/kg CO. Treatment with CO increased the relative weight of spleen, thymus, bursa of Fabricius and plasma content of IgM when compared to the control and the antibiotic-treated groups. In chickens fed CO a significant decrease in caecal total microbial count, total yeast and mold count, Escherichia coli, and Salmonella was noted in comparison with the control group but was similar to animals from antibiotic-treated group. The count of lactic acid bacteria increased in the caecum of chickens fed CO in comparison with those from the control group; the lowest level was observed in the antibiotic group. So, CO can be used in broiler chicken diets as a natural alternative to antibiotic growth promoters to improve gut health and consequently growth performance.
This work was supported by the Poultry Department, Faculty of Agriculture, Zagazig University, Egypt. All the authors of the manuscript thank and acknowledge their respective Universities and Institutes. The English revision of the manuscript conducted by Mr. Roderick Cantlay-Hollis is also acknowledged.
This study was partially supported by the Faculty of Agriculture, Zagazig University, Egypt.
The authors declare that there is no conflict of interest.
肉桂油对肉鸡生长、胴体性状、血液生化指标、免疫功能、 抗氧化状态和盲肠微生物数量的影响
摘要:本研究旨在探讨肉桂油(cinnamon oil、CO)对肉鸡生长性能、胴体性状、血液生化参数、免疫功能、 抗氧化状态和盲肠微生物计数的影响。将300只1日龄肉仔鸡随机分为5组(每个重复12只)。日粮处理包括 基础日粮(对照组),基础日粮中添加10 mg/kg阿维拉霉素(抗生素组)和CO添加分别为500 mg/kg、1000 mg/kg 和1500 mg/kg 剂量组(CO组)。结果表明,与对照组相比,CO组的肉仔鸡具有更高的体重、增重和 饲料转化率。此外,与对照组相比,CO组的肉仔鸡总胆固醇、甘油三酯、低密度脂蛋白较低;与对照组和 抗生素治疗组相比,添加500 mg/kg 的CO组的上述参数值最低。添加CO增加了肉仔鸡脾脏、胸腺、法氏囊 的相对重量和血浆IgM含量。与对照组相比,CO组的肉仔鸡盲肠微生物总数、酵母菌和霉菌总数、大肠杆 菌和沙门氏菌显著减少,但与抗生素组相比结果相似。与对照组相比,CO组的肉仔鸡盲肠内乳酸菌数量增 加;抗生素组最低。因此,肉桂油可以作为抗生素促生长添加剂的天然替代品用于肉鸡日粮中,以改善肠 道健康,从而提高生长性能。
Abd El-Hack M.E., Alagawany M., Abdel-Moneim A.M.E., Mohammed N.G., Khafaga A.F., Bin-Jumah M., Othman S.I., Allam A.A., Elnesr S.S., 2020. Cinnamon (Cinnamomum zeylanicum) oil as a potential alternative to antibiotics in poultry. Antibiotics 9, 1–12, https://doi.org/10.3390/antibi....
Abo Ghanima M.M., Elsadek M.F., Taha A.E., Abd El-Hack M.E., Alagawany M., Ahmed B.M., Elshafie M.M., El-Sabrout K., 2020. Effect of housing system and rosemary and cinnamon essential oils on layers performance, egg quality, haematological traits, blood chemistry, immunity, and antioxidant. Animals 10, https://doi.org/10.3390/ani100....
Adams R.P., 2017. Identification of Essential Oil Components by Gas Chromatography/Mass Spectrometry, 5th online edition. Texensis Publishing, Gruver, TX (USA).
Aebi H., 1984. Catalase in vitro. In: Methods Enzymol. Elsevier. 105, 121–126, https://doi.org/10.1016/S0076-....
Ahmed E., Attia A., Ibrahem Z., Abd El-Hack M., 2019. Effect of dietary ginger and cinnamon oils supplementation on growing japanese quail performance. Zagazig J. Agric. Res. 46, 2037–2046, https://doi.org/10.21608/zjar.....
Al-Kassie G.A.M., 2009. Influence of two plant extracts derived from thyme and cinnamon on on broiler performance. Pakist. Vet. J. 29, 169–173.
Alagawany M., Abd El-Hack M.E., Saeed M. et al., 2020. Nutritional applications and beneficial health applications of green tea and L-Theanine in some animal species: A Review. J. Anim. Physiol. Anim. Nutr. 104, 245–256, https://doi.org/10.1111/jpn.13....
Alagawany M., Farag M.R., El-Kholy M.S., El-Sayed S.A.A., Dhama K., 2017. Effect of resveratrol, cinnamaldehyde and their combinations on the antioxidant defense system and atp release of rabbit erythrocytes: in vitro study. Asian J. Anim Vet. Adv. 12, 1–9, https://doi.org/10.3923/ajava.....
Ali M., Ismail Z., Ali A., Sultan S., 2018. Physiological responses and productive performance of broiler chicks fed diets supplemented with different levels of cinnamon powder. Egypt. Poult. Sci. J. 38, 1171–1184, https://doi.org/10.21608/epsj.....
Al-Shuwaili M.A., Ibrahim E.I., Naqi Al-Bayati M.T., 2015. Effect of dietary herbal plants supplement in turkey diet on performance and some blood biochemical parameters. Glob. J. Biosci. Biotechnol. 4, 153–157.
Anthony A., Anthony I., Steve J., 2010. Studies on multiple antibiotic resistant bacterial isolated from surgical site infection. Sci. Res. Essays 5, 3876–3881.
Basílico M.Z., Basílico J.C., 1999. Inhibitory effects of some spice essential oils on Aspergillus ochraceus NRRL 3174 growth and ochratoxin A production. Lett. Appl. Microbiol. 29, 238–241, https://doi.org/10.1046/j.1365....
Bento M.H.L., Ouwehand A.C., Tiihonen K., Lahtinen S., Nurminen P., Saarinen M.T., Schulze H., Mygind T. Fischer J., 2013. Essential oils and their use in animal feeds for monogastric animals–Effects on feed quality, gut microbiota, growth performance and food safety: a review. Vet. Med. 58, https://doi.org/10.17221/7029-....
Beutler E., 1963. Improved method for the determination of blood glutathione. J. Lab. Clin. Med. 61, 882–888.
Bianchi A.T.J., Moonen-Leusen H.W.M., van der Heijden P.J., Bokhout B.A., 1995. The use of a double antibody sandwich ELISA and monoclonal antibodies for the assessment of porcine IgM, IgG and IgA concentrations. Vet. Immunol. Immunopathol. 44,.309–317, https://doi.org/10.1016/0165-2...
Campbell T.W., 1995. Avian hematology and cytology. 2nd Edition. Iowa State University Press. Ames. IA (USA).
Cao H., Urban J.F., Anderson R.A., 2008. Cinnamon polyphenol extract affects immune responses by regulating anti- and proinflammatory and glucose transporter gene expression in mouse macrophages. J. Nutr. 138, 833–840, https://doi.org/10.1093/jn/138....
Chowdhury S., Mandal G.P., Patra A.K., Kumar P., Samanta I., Pradhan S., Samanta A.K., 2018. Different essential oils in diets of broiler chickens: 2. Gut microbes and morphology, immune response, and some blood profile and antioxidant enzymes. Anim. Feed Sci. Technol. 236, 39–47, https://doi.org/10.1016/j.anif....
Ciftci M., Dalkilic B., Cerci I.H., Guler T., Ertas O.N., Arslan O., 2009. Influence of dietary cinnamon oil supplementation on performance and carcass characteristics in broilers. J. Appl. Anim. Res. 36, 125–128, https://doi.org/10.1080/097121....
Ciftci M., Simsek U.G., Yuce A., Yilmaz O., Dalkilic B., 2010. Effects of dietary antibiotic and cinnamon oil supplementation on antioxidant enzyme activities, cholesterol levels and fatty acid compositions of serum and meat in broiler chickens. Acta Vet. Brno. 79, 33–40, https://doi.org/10.2754/avb201....
Dorman H.J.D., Deans S.G., 2000. Antimicrobial agents from plants: Antibacterial activity of plant volatile oils. J. Appl. Microbiol. 88, 308–316, https://doi.org/10.1046/j.1365....
Elson C.E., Underbakke G.L., Hanson P., Shrago E., Wainberg R.H., Qureshi A.A., 1989. Impact of lemongrass oil, an essential oil, on serum cholesterol. Lipids 24, 677–679, https://doi.org/10.1007/BF0253....
Fki I., Bouaziz M., Sayadi S., 2005. Hypocholesterolemic effects of phenolic-rich extracts of Chemlali olive cultivar in rats fed a cholesterol-rich diet. Bioorg. Med. Chem. 13, 5362–5370, https://doi.org/10.1016/j.bmc.....
Friedewald W.T., Levy R.I., Fredrickson D.S., 1972. Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge. Clin. Chem. 18, 499–502, https://doi.org/10.1093/clinch....
Goldstein J.L., Brown M.S., 1995. Regulation of the mevalonate pathway in plants. Nature 343, 425–430, https://doi.org/10.1038/343425....
Gomathi G., Senthilkumar S., Natarajan A., Amutha R., Purushothaman M.R., 2018. Effect of dietary supplementation of cinnamon oil and sodium butyrate on carcass characteristics and meat quality of broiler chicken. Vet. World. 11, 959–964, https://doi.org/10.14202/vetwo....
Harrigan W.F., McCance. M.E., 1990. Laboratory methods in food and dairy microbiology, Academic Press Inc. London, United Kingdom.
Hernández F., Madrid J., García V., Orengo J., Megías M.D., 2004. Influence of two plant extracts on broilers performance, digestibility, and digestive organ size. Poult. Sci. 83, 169–174, https://doi.org/10.1093/ps/83.....
Hsu D.-Z., Liu M.-Y., 2004. Sesame oil protects against lipopolysaccharide-stimulated oxidative stress in rats. Crit. Care Med. 32, 227–231, https://doi.org/10.1097/01.CCM....
Jamroz D., Wertelecki T., Houszka M., Kamel C., 2006. Influence of diet type on the inclusion of plant origin active substances on morphological and histochemical characteristics of the stomach and jejunum walls in chicken. J. Anim. Physiol. Anim. Nutr. (Berl). 90, 255–268, https://doi.org/10.1111/j.1439....
Jamroz D., Wiliczkiewicz A., Wertelecki T., Orda J., Skorupińska J., 2005. Use of active substances of plant origin in chicken diets based on maize and locally grown cereals. Br. Poult. Sci. 46, 485–493, https://doi.org/10.1080/000716....
Kanani B., Daneshyar P., Najafi M., 2016. Effects of cinnamon (Cinnamomum zeylanicum) and turmeric (Curcuma longa) powders on performance, enzyme activity, and blood parameters of broiler chickens under heat stress. Poult. Sci. J. 1, 47–53, https://doi.org/10.22069/PSJ.2....
Khafaji S., 2018. Study the effect of ceylon cinnamon (cinnamomumzeylanicum) powder on some physiological parameters in broiler chicks. J. Global Pharma. Technol. 10, 236–242.
Koracevic D., Koracevic G., Djordjevic V., Andrejevic S., Cosic V., 2001. Method for the measurement of antioxidant activity in human fluids. J. Clin. Pathol. 54, 356–361, https://doi.org/10.1136/jcp.54....
Krishan G. Narang A., 2014. Use of essential oils in poultry nutrition: A new approach. J. Adv. Vet. Anim. Res. 1, 156–162 https://doi.org/10.5455/javar.....
Kurtzman C., Fell J.W., Boekhout T., 2011. The yeasts: a taxonomic study. 5th Edition, Elsevier, USA.
Langhout P., 2000. New additives for broiler chickens. World Poultr. 16, 22–27.
Lee M.K., Park Y.B., Moon S.S., Bok S.H., Kim D.J., Ha T.Y., Jeong T.S., Jeong K.S., Choi M.S., 2007. Hypocholesterolemic and antioxidant properties of 3-(4-hydroxyl) propanoic acid derivatives in high-cholesterol fed rats. Chem. Biol. Interact.170, 9–19, https://doi.org/10.1016/j.cbi.....
Mehdipour Z., Afsharmanesh M., 2018. Evaluation of synbiotic and cinnamon (Cinnamomum verum) as antibiotic growth promoter substitutions on growth performance, intestinal microbial populations and blood parameters in Japanese quail. J. Livest. Sci. Technol. 6, 1–8, https://doi.org/10.22103/jlst.....
Mellor S., 2000. Antibiotics are not the only growth promoters. World Poultr. 16, 14–15.
Nishikimi M., Rao N.A., Yagi K., 1972. The occurrence of superoxide anion in the reaction of reduced phenazine methosulfate and molecular oxygen. Biochem. Biophys. Res. Commun. 46, 849–854, https://doi.org/10.1016/S0006-....
NRC (National Research Council), 1994. Nutrient Requirements of Poultry. 9th Revised Edition. The National Academies Press. Washington, DC (USA), https://doi.org/10.17226/2114.
Ohkawa H., Ohishi N., Yagi K., 1979. Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Anal. Biochem. 95, 351–358, https://doi.org/10.1016/0003-2....
Oussalah M., Caillet S., Lacroix M., 2006. Mechanism of action of Spanish oregano, Chinese cinnamon, and savory essential oils against cell membranes and walls of Escherichia coli O157:H7 and Listeria monocytogenes. J. Food Prot. 69, 1046–1055, https://doi.org/10.4315/0362-0....
Paglia D.E., Valentine W.N., 1967. Studies on the quantitative and qualitative characterization of erythrocyte glutathione peroxidase. J. Lab. Clin. Med. 70, 158–169, https://doi.org/10.5555/uri:pi...
Peñalver P., Huerta B., Borge C., Astorga R., Romero R., Perea A., 2005. Antimicrobial activity of five essential oils against origin strains of the Enterobacteriaceae family. Apmis. 113, 1–6, https://doi.org/10.1111/j.1600....
Ravis W.R., Parsons D.L., Wang S.J., 1988. Buffer and pH Effects on Propranolol Binding by Human Albumin and α1-acid Glycoprotein. J. Pharm. Pharmacol. 40, 459–463, https://doi.org/10.1111/j.2042....
Reda F.M., Alagawany M., Mahmoud H.K., Mahgoub S.A., Elnesr S.S., 2020a. Use of red pepper oil in quail diets and its effect on performance, carcass measurements, intestinal microbiota, antioxidant indices, immunity and blood constituents. Animal.14, 1025–1033, https://doi.org/10.1017/S17517....
Reda F.M., El-Kholy M.S., Abd El-Hack M.E., Taha A.E., Othman S.I., Allam A.A., Alagawany M., 2020b. Does the use of different oil sources in quail diets impact their productive and reproductive performance, egg quality, and blood constituents? Poult. Sci. 99, 3511–3518, https://doi.org/10.1016/j.psj.....
Reda F.M., El-Saadony M.T., Elnesr S.S., Alagawany M., Tufarelli V., 2020c. Effect of dietary supplementation of biological curcumin nanoparticles on growth and carcass traits, antioxidant status, immunity and caecal microbiota of Japanese quails. Animals 10, 754, https://doi.org/10.3390/ani100....
Sang-Oh P., Chae-Min R., Byung-Sung P., Jong H., 2013. The meat quality and growth performance in broiler chickens fed diet with cinnamon powder. J. Environ. Biol. 34, 127–133, https://pubmed.ncbi.nlm.nih.go...
Sarica S., Corduk M., Yarim G.F., Yenisehirli G., Karatas U., 2009. Effects of novel feed additives in wheat based diets on performance, carcass and intestinal tract characteristics of quail. South African J. Anim. Sci. 39, 144–157, https://doi.org/10.4314/sajas.....
SAS, User’s guide: Basics. Institute Statistical Analysis System. Cary, North Carolina. SMN. 2014. Unidad del Servicio Meteorológico Nacional, CNA.
Schalm O.W., 1961. Veterinary hematology. Lea and Febiger. Publisher, Philadelphia, PA (USA), pp.165–187.
Symeon G.K., Athanasiou A., Lykos N., Charismiadou M.A., Goliomytis M., Demiris N., Ayoutanti A., Simitzis P.E., Deligeorgis S.G., 2014. The effects of dietary cinnamon (Cinnamomum zeylanicum) oil supplementation on broiler feeding behaviour, growth performance, carcass traits and meat quality characteristics. Ann. Anim. Sci. 14, 883–895, https://doi.org/10.2478/aoas-2....
Tiihonen K., Kettunen H., Bento M.H.L., Saarinen M., Lahtinen S., Ouwehand A.C., Schulze H., Rautonen N., 2010. The effect of feeding essential oils on broiler performance and gut microbiota. Br. Poult. Sci. 51, 381–392, https://doi.org/10.1080/000716....
Tiwari R., Latheef S.K., Ahmed I. Iqbal H.M.N., Bule M.H., Dhama K., Samad H.A., Alagawany M., El-Hack M.E.A., Yatoo M.I., Farag M.R., 2018. Herbal immunomodulators, a remedial panacea for the designing and developing effective drugs and medicines: Current scenario and future prospects. Curr. Drug Metabol. 19, 264–301, https://doi.org/10.2174/138920....
Toghyani M., Toghyani M., Gheisari A., Ghalamkari G., Eghbalsaied S., 2011. Evaluation of cinnamon and garlic as antibiotic growth promoter substitutions on performance, immune responses, serum biochemical and haematological parameters in broiler chicks. Livest. Sci. 138, 167–173, https://doi.org/10.1016/j.livs....
Torki M., Sedgh-Gooya S., Mohammadi H., 2018. Effects of adding essential oils of rosemary, dill and chicory extract to diets on performance, egg quality and some blood parameters of laying hens subjected to heat stress. J Appl. Anim. Res. 46, 1118–1126, https://doi.org/10.1080/097121....
Valero M., Salmero M.C., 2003. Antibacterial activity of 11 essential oils against Bacillus cereus in tyndallized carrot broth. Inter. J. food Microbiol. 85, 73–81, https://doi.org/10.1016/S0168-....
Yang Y.F., Zhao L. Lu., Shao Y. Xin., Liao X. Dong., Zhang L. Yang., Lu L., Luo X Gang., 2019. Effects of dietary graded levels of cinnamon essential oil and its combination with bamboo leaf flavonoid on immune function, antioxidative ability and intestinal microbiota of broilers. J. Integr. Agric. 18, 2123–2132, https://doi.org/10.1016/S2095-....
Zhou T.X., Chen Y.J., Yoo J.S., Huang Y., Jee J.H., Jang H.D., Shin S.O., Kim H.J., Cho J.H., Kim I.H. 2009. Effects of chitooligosaccharide supplementation on performance, blood characteristics, relative organ weight, and meat quality in broiler chickens. Poult. Sci. 88, 593–600, https://doi.org/10.3382/ps.200....
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