Inulin-type fructans trigger changes in iron concentration and activity of bone metabolism biomarkers in blood plasma of growing pigs
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West Pomeranian University of Technology Szczecin, Department of Physiology, Cytobiology and Proteomics, Doktora Judyma 6, 71-466 Szczecin, Poland
The Kielanowski Institute of Animal Physiology and Nutrition, Polish Academy of Sciences, Instytucka 3, 05-110 Jabłonna, Poland
Publication date: 2016-12-02
Corresponding author
A. Lepczyński   

West Pomeranian University of Technology Szczecin, Department of Physiology, Cytobiology and Proteomics, Doktora Judyma 6, 71-466 Szczecin, Poland
J. Anim. Feed Sci. 2016;25(4):343-347
The aim of the study was to estimate the influence of dietary supplementation with dried chicory root and native chicory inulin on biochemical profile of blood plasma. In total 24 male piglets were divided into 3 groups (n = 8) and fed unsupplemented cereal-based diet (C diet), diet with 2% of native chicory inulin (T1 diet) or with 4% of dried chicory root (T2 diet). After 40 days of feeding pigs were sacrificed and blood plasma samples were taken for biochemical analysis. Plasma albumin concentration, as well as alkaline phosphatase and alanine aminotransferase activity, were significantly higher in the group of animals fed T2 diet. Plasma γ-glutamyltransferase activity was significantly lower in the pigs fed T2 diet when compared to animals fed C and T1 diets. Significant increase in plasma iron concentration in animals fed T2 diet and slightly increased calcium level in both treatment groups were observed. It can be concluded that dietary fructans and dried chicory root do not affect liver functioning. Feeding growing pigs diet supplemented with dried chicory root significantly improves plasma iron concentration and may increase blood plasma calcium concentration what, in turn, may enhance bone mineralization and growth in young animals.
Abrams S.A., Griffin I.J., Hawthorne K.M., Liang L., Gunn S.K., Darlington G., Ellis K.J., 2005. A combination of prebiotic short- and long-chain inulin-type fructans enhances calcium absorption and bone mineralization in young adolescents. Am. J. Clin. Nutr. 82, 471–476
Chen C.-H., Ho M.-L., Chang J.-K., Hung S.-H., Wang G.-J., 2005. Green tea catechin enhances osteogenesis in a bone marrow mesenchymal stem cell line. Osteoporos. Int. 16, 2039–2045,
Cheng G., Hao H., Xie S., Wang X., Dai M., Huang L., Yuan Z., 2014. Antibiotic alternatives: the substitution of antibiotics in animal husbandry? Front. Microbiol. 5, 217,
Gibson G.R., Roberfroid M.B., 1995. Dietary modulation of the human colonic microbiota: introducing the concept of prebiotics. J. Nutr. 125, 1401-1412
Hassan H.A., Yousef M.I., 2010. Ameliorating effect of chicory (Cichorium intybus L.)-supplemented diet against nitrosamine precursors- induced liver injury and oxidative stress in male rats. Food Chem. Toxicol. 48, 2163–2169,
Kang K.-S., 2013. Abnormality on liver function test. Pediatr. Gastroenterol. Hepatol. Nutr. 16, 225–232,
Lepczynski A., Herosimczyk A., Ozgo M., Skomial J., Taciak M., Barszcz M., Berezecka N., 2015. Dietary supplementation with dried chicory root triggers changes in the blood serum proteins engaged in the clotting process and the innate immune response in growing pigs. J. Physiol. Pharmacol. 66, 47–55
Lepczyński A., Herosimczyk A., Ożgo M., Marynowska M., Pawlikowska M., Barszcz M., Taciak M., Skomiał J., 2016. Dietary chicory root and chicory inulin trigger changes in energetic metabolism, stress prevention and cytoskeletal proteins in the liver of growing pigs – a proteomic study. J. Anim. Physiol. Anim. Nutr. [Epub ahead of print, 17.11.2016]
Nasiri A., Ziamajidi N., Behrouj H., Abbasalipourkabir R., Dehghan A., 2014. The effects of aqueous extract of chicory root on steatosis, lipid profile and liver damage enzyme markers in tamoxifen- treated rats. Mol. Biochem. Diag. 1, 185–194
Scholz-Ahrens K., Açil Y., Schrezenmeir J., 2002. Effect of oligofructose or dietary calcium on repeated calcium and phosphorus balances, bone mineralization and trabecular structure in ovariectomized rats. Br. J. Nutr. 88, 365–377,
Scholz-Ahrens K.E., Schrezenmeir J., 2007. Inulin and oligofructose and mineral metabolism: the evidence from animal trials. J. Nutr. 137, 2513S–2523S
Seifert S., Watzl B., 2007. Inulin and oligofructose: review of experimental data on immune modulation. J. Nutr. 137, 2563S–2567S
Smink J.J., Buchholz I.M., Hamers N., van Tilburg C.M., Christis C., Sakkers R.J.B., de Meer K., van Buul-Offers S.C., Koedam J.A., 2003. Short-term glucocorticoid treatment of piglets causes changes in growth plate morphology and angiogenesis. Osteoarthr. Cartil. 11, 864–871,
Tako E., Glahn R.P., Welch R.M., Lei X., Yasuda K., Miller D.D., 2008. Dietary inulin affects the expression of intestinal enterocyte iron transporters, receptors and storage protein and alters the microbiota in the pig intestine. Br. J. Nutr. 99, 472–480,
Tymczyna B., Tatara M.R., Krupski W., Tymczyna-Sobotka M., Łuszczewska-Sierakowska I., Bachanek T., 2012. Relationships between biochemical bone metabolism indices and morphometric, densitometric and mechanical properties of mandible in 6-month-old pigs. Ann. Agric. Environ. Med. 19, 535–539
Van Hoof V.O., Hoylaerts M.F., Geryl H., Van Mullem M., Lepoutre L.G., De Broe M.E., 1990. Age and sex distribution of alkaline phosphatase isoenzymes by agarose electrophoresis. Clin. Chem. 36, 875–878
Yasuda K., Dawson H.D., Wasmuth E.V., Roneker C.A., Chen C., Urban J.F., Welch R.M., Miller D.D., Lei X.G., 2009. Supplemental dietary inulin influences expression of iron and inflammation related genes in young pigs. J. Nutr. 139, 2018–2023,
Yasuda K., Roneker K.R., Miller D.D., Welch R.M., Lei X.G., 2006. Supplemental dietary inulin affects the bioavailability of iron in corn and soybean meal to young pigs. J. Nutr. 136, 3033–3038
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