ORIGINAL PAPER
Effect of different feed physical forms (pellet, crumble, mash) on the performance and liver health in broiler chicken with and without carbon tetrachloride challenge
 
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Lorestan University, Faculty of Agriculture, Department of Animal Sciences, P.B. 465, Khorramabad 68137-17133, Lorestan, Iran
 
 
Publication date: 2020-03-31
 
 
Corresponding author
H. Khosravinia   

Lorestan University, Faculty of Agriculture, Department of Animal Sciences, P.B. 465, Khorramabad 68137-17133, Lorestan, Iran
 
 
J. Anim. Feed Sci. 2020;29(1):59-66
 
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ABSTRACT
A study was carried out to investigate the effects of physical feed form on productive performance and liver function in broiler chickens toxified or not with carbon tetrachloride (CCl4). The experiment was conducted on 468 ten-day-old broiler chickens fed with mash, crumble and pelleted diets from day 11 to 42 of age. Birds from toxified groups were three times intramuscularly injected with CCl4 (0.5, 0.5 and 0.75 ml/kg body weight) at day 14, 21 and 28 of age, respectively. The main factors interaction showed that daily weight gain of birds fed with pelleted diet was higher in comparison with those grown on crumble and mash diets but only when birds were challenged with CCl4. The feed physical form influenced European production efficiency index with higher values observed for birds fed with pelleted diet from day 29 to 42 of age. Liver fat percentage increased by 2.06% in birds fed with pelleted diet compared with those grown on mash one. Broilers offered pelleted diet showed greater serum low-density lipoprotein cholesterol concentration compared with those fed with crumble diet but only when birds were challenged with CCl4. The frequency of score zero indicating liver with no visible injuries was greater in broilers fed with crumble diet (58.33%) than in those receiving mash and pelleted diets after 31-day feeding period. In summary, the feed physical form can affect broiler growth performance and blood biochemical parameters in broilers subjected to CCl4 challenge. However, further studies using higher doses of CCl4 should be conducted to induce more pronounced liver dysfunction in experimental birds.
 
REFERENCES (33)
1.
Amerah A.M., Ravindran V., Lentle R.G., Thomas D.G., 2008. Influence of feed particle size on the performance, energy utilization, digestive tract development, and digesta parameters of broiler starters fed wheat- and corn-based diets. J. Poult. Sci. 87, 2320–2328, https://doi.org/10.3382/ps.200....
 
2.
Babin P.J., Gibbons G.F., 2009. The evolution of plasma cholesterol: direct utility or a “spandrel” of hepatic lipid metabolism? Prog. Lipid Res. 48, 73–91, https://doi.org/10.1016/j.plip....
 
3.
Bellassoued K., Ben Hsouna A., Athmouni K., van Pelt J., Makni Ayadi F., Rebai T., Elfeki A., 2018. Protective effects of Mentha piperita L. leaf essential oil against CCl4 induced hepatic oxidative damage and renal failure in rats. Lipids Health Dis. 17, 9, https://doi.org/10.1186/s12944....
 
4.
Boll M., Lutz W.D., Becker E., Stampfl A., 2001. Mechanism of carbon tetrachloride-induced hepatotoxicity. Hepatocellular damage by reactive carbon tetrachloride metabolites. Z. Naturforsch. C. 56, 649–659, https://doi.org/10.1515/znc-20....
 
5.
Clawson G.A., 1989. Mechanisms of carbon tetrachloride hepatotoxicity. Pathol Immunopathol. Res. 8, 104–112, https://doi.org/10.1159/000157....
 
6.
Ebrahimi R., Bojar Pour M., Mokhtar Zadeh S., 2010. Effect of feed particle size on the performance and carcass characteristics of broilers. J. Anim. Vet. Adv. 9, 1482–1484, https://doi.org/10.3923/javaa.....
 
7.
Elliott R.J., 1984. Ektachem DT-60 Analyzer. Physician Leading Comput. J. 2, 6.
 
8.
Euribrid B.V., 1994. Technical information for Hybro broilers. Euribrid Poultry Breeding Farm. Boxmeer (The Netherlands), pp. 22.
 
9.
Folch J., Lees M., Sloane Stanley G.H., 1957. A simple method for the isolation and purification of total lipides from animal tissues. J. Biol. Chem. 226, 497–509.
 
10.
Hünigen H., Mainzer K., Hirschberg R.M., Custodis P., Gemeinhardt O., Al Masri S., Richardson K.C., Hafez H.M., Plendl J., 2016. Structure and age-dependent development of the turkey liver: a comparative study of a highly selected meat-type and a wild-type turkey line. Poult. Sci. 95, 901–911, https://doi.org/10.3382/ps/pev....
 
11.
Jafarnejad S., Farkhoy M., Sadegh M., Bahonar A.R., 2010. Effect of crumble-pellet and mash diets with different levels of dietary protein and energy on the performance of broilers at the end of the third week. Vet. Med. Int. 2010, 328123, https://doi.org/10.4061/2010/3....
 
12.
Khodadust M.R., Samadi F., Ganji F., Ahangari J., Asadi G.H., 2015. Effects of peppermint (Mentha piperita L.) alcoholic extract on carbon tetrachloride-induced hepatotoxicity in broiler chickens under heat stress condition. Poult. Sci. J. 3, 1–16, https://doi.org/10.22069/PSJ.2....
 
13.
Khoramshahi M., Samadi F., 2015. Toxicity of carbon tetrachloride in Japanese quails: evaluation the effect of artichoke (Cynara scolymus) powder on performance and immune response. Iran. J. Appl. Anim. Sci. 5, 417–422.
 
14.
Kramer C.Y., 1956. Extension of multiple range tests to group means with unequal numbers of replications. Biometrics 12, 307–310, https://doi.org/10.2307/300146....
 
15.
Li G.-Y., Gao H.-Y., Huang J., Lu J., Gu J.-K., Wang J.-H., 2014. Hepatoprotective effect of Cichoriumin tybus L., a traditional Uighur medicine, against carbon tetrachloride-induced hepatic fibrosis in rats. World J. Gastroenterol. 20, 4753–4760, https://doi.org/10.3748/wjg.v2....
 
16.
Lin H.-M., Tseng H.-C., Wang C.-J., Lin J.-J., Lo C.-W., Chou F.-P., 2008. Hepatoprotective effects of Solanum nigrum Linn extract against CCl4-induced oxidative damage in rats. Chem. Biol. Interact. 171, 283–293, https://doi.org/10.1016/j.cbi.....
 
17.
Liu B., Fang Y., Yi R., Zhao X., 2019. Preventive effect of blueberry extract on liver injury induced by carbon tetrachloride in mice. Foods 8, 48, https://doi.org/10.3390/foods8....
 
18.
Owen J.S., 1990. Extrahepatic cell membrane lipid abnormalities and cellular dysfunction in liver disease. Drugs 40, 73–83, https://doi.org/10.2165/000034....
 
19.
Ozougwu J.C., Eyo J.E., 2014. Hepatoprotective effects of Allium cepa (onion) extracts against paracetamol-induced liver damage in rats. Afr. J. Biotechnol. 13, 2679–2688, https://doi.org/10.5897/AJB201....
 
20.
Panovska T., Kulevanova S., Gjorgoski I., Bogdanova M., Petrushevska G., 2007. Hepatoprotective effect of the ethyl acetate extract of Teucrium polium L. against carbontetrachloride-induced hepatic injury in rats. Acta Pharm. 57, 241–248, https://doi.org/10.2478/v10007....
 
21.
Parmar M.Y., Shah P.A., Thakkar V.T., Al-Rejaie S.S., Gandhi T.R., 2012. Hepatoprotective effect of amomum subulatum roxb seeds on carbon tetrachloride-induced liver damage in rats. J. Pharm. 2, 38–43, https://doi.org/10.9790/3013-2....
 
22.
Samudram P., Rajeshwari H., Vasuki R., Geetha A., Sathiya Moorthi P., 2008. Hepatoprotective activity of Bi-herbal ethanolic extract on CCl4 induced hepatic damage in rats. Asian J. Biochem. 3, 308–314, https://doi.org/10.3923/ajb.20....
 
23.
Shah M.D., D’Souza U.J.A., Iqbal M., 2017. The potential protective effect of Commelina nudiflora L. against carbon tetrachloride (CCl4)-induced hepatotoxicity in rats, mediated by suppression of oxidative stress and inflammation. Environ. Health Prev. Med. 22, 66, https://doi.org/10.1186/s12199....
 
24.
Shen B., Chen H., Shen C., Xu P., Li J., Shen G., Yuan H., Han J., 2015. Hepatoprotective effects of lignans extract from Herpetospermum caudigerum against CCl4-induced acute liver injury in mice. J. Ethnopharmacol. 164, 46–52, https://doi.org/10.1016/j.jep.....
 
25.
Shini A., 2014. Fatty liver haemorrhagic syndrome in laying hens: field and experimental investigations, PhD Thesis. University of Queensland. St. Lucia (Australia).
 
26.
Sobrane Filho S.T., Junqueira O.M., de Laurentiz A.C., da Silva Filardi R., da Silva Rubio M., Duarte K.F., da Silva de Laurentiz R., 2016. Effects of mycotoxin adsorbents in aflatoxin B1- and fumonisin B1-contaminated broiler diet on performance and blood metabolite. Rev. Bras. Zootec. 45, 250–256, https://doi.org/10.1590/S1806-....
 
27.
Sonkusale P., Bhandarker A.G., Kurkare N.V., Ravikanth K., Maini S., Sood D., 2011. Hepatoprotective activity of superliv liquid and repchol in CCl4 induced FLKS syndrome in broilers. Int. J. Poult. Sci. 10, 49–55, https://doi.org/10.3923/ijps.2....
 
28.
Svihus B., Kløvstad K.H., Perez V., Zimonja O., Sahlström S., Schüller R.B., Jeksrud W.K., Prestløkken E., 2004. Physical and nutritional effects of pelleting of broiler chicken diets made from wheat ground to different coarsenesses by the use of roller mill and hammer mill. Anim. Feed. Sci. Technol. 117, 281–293, https://doi.org/10.1016/j.anif....
 
29.
Tedesco D., 2001. The potentiality of herbs and plant extracts as feed additives in livestock production (in Italian: Il potenziale ruolo di erbe ed estratti naturali utilizzati come additivi alimentari nelle produzioni animali). Zootec. Nutr. Anim. 27, 111–133.
 
30.
Trott K.A., Giannitti F., Rimoldi G., Hill A., Woods L., Barr B., Anderson M., Mete A., 2014. Fatty liver hemorrhagic syndrome in the backyard chicken: A retrospective histopathologic case series. Vet. Pathol. 51, 787–795, https://doi.org/10.1177/030098....
 
31.
Wang C., Zhang T., Cui X., Li S., Zhao X., Zhong X., 2013. Hepatoprotective effects of a Chinese herbal formula, Longyin decoction, on carbon-tetrachloride-induced liver injury in chickens. Evid. Based Complement. Alternat. Med. 20133, 392743, https://doi.org/10.1155/2013/3....
 
32.
Yang Y.-S., Ahn T.-H., Lee J.-C., Moon C.-J., Kim S.-H., Jun W., Park S.-C., Kim H.-C., Kim J.-C., 2008. Protective effects of Pycnogenol on carbon tetrachloride-induced hepatotoxicity in Sprague-Dawley rats. Food Chem. Toxicol. 46, 380–387, https://doi.org/10.1016/j.fct.....
 
33.
Yang C., Gong X., Ai Q., Ge P., Lin L., Zhang L., 2015. 5-Aminoimidazole-4-carboxamide-1-β-D-ribofuranoside alleviated carbon tetrachloride-induced acute hepatitis in mice. Int. J. Immunopharmacol. 25, 393–399, https://doi.org/10.1016/j.inti....
 
 
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ISSN:1230-1388
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