ORIGINAL PAPER
Impact of DDT residues in feed on thyroid gland and liver secretory activity of Aberdeen-Angus cattle depending on cattle age and sex
1
South Ural State Agrarian University, st. Gagarina 13, 457100, Troitsk,
Chelyabinsk Region, Russia
2
Republican Veterinary Laboratory of the Committee for Veterinary Control and Supervision of the Ministry of Agriculture of the Republic of Kazachstan, st. Zarechnoye, Yubileynaya 5a, 111108, Kostanay, Kazachstan
3
Institute of Plant Protection - National Research Institute, st. Chelmonskiego 22, 15-195, Bialystok, Poland
Publication date: 2020-11-30
Corresponding author
B. Lozowicka
Institute of Plant Protection - National Research Institute, st. Chelmonskiego 22, 15-195, Bialystok, Poland
Institute of Plant Protection - National Research Institute, st. Chelmonskiego 22, 15-195, Bialystok, Poland
J. Anim. Feed Sci. 2020;29(4):306-315
KEYWORDS
TOPICS
ABSTRACT
Dichlorodiphenyltrichloroethane (DDT) and its metabolites are
constantly detected in agricultural crops intended for animal feed. The aim
of this study was to evaluate the impact of DDT residues in feed on thyroid
gland and liver secretory activity of Aberdeen-Angus cattle depending on
cattle age and sex. DDT (sum) concentration in the forage (milk, hay, silage,
compound feed) and soil was determined by gas chromatography with micro
electron capture selective detector (GC/ECD), while thyroid gland hormones
(triiodothyronine (T3), thyroxine (T4)) concentrations and liver enzymes (alanine
aminotransferase, aspartate aminotransferase, alkaline phosphatase, creatine
kinase, lactate dehydrogenase) activities using ELISA, based on colorimetric
method. It was indicated that natural contamination of soil and, in consequence,
feed with DDT is diversed and was the highest in milk. Concentration of T3
decreased during bulls growth reaching the lowest level in 8-month animals
(1.92 pmol/l), while content of T4 was raising and achieved the highest content
in 8-month bulls (129.07 pmol/l). Opposite relation was observed in heifers
(increasing content of T3 and falling level of T4). Liver enzymes activity was
also depended on cattle age and sex. However, concentrations of thyroid
hormones and activities of liver enzymes were significantly higher (P < 0.05) in
bulls and heifers fed forage containing DDT. DDT contamination of feed leads
to hypothyroid in bulls and hyperthyroid in heifers in long-term intake. Milk,
which is given to the calves at the beginning of the nursing period should be
especially examined for DDT residues occurrence because young animals are
particularly susceptible to endocrine and liver disorders.
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