1.054
IF5
1.150
IF
Q3
JCR
1.7
CiteScore
0.396
SJR
Q2
SJR
40
MNiSW
148.75
ICV
ORIGINAL PAPER
 
CC-BY 4.0
 
 

Changes in integrin-positive cells and T cell subpopulations in the peripheral blood and intestine of calves fed soya protein

M. Brna 1,  
V. Revajová 2,  
R. Žitňan 1  ,  
M. Levkut Jr. 2,  
M. Baran 3,  
 
1
Animal Production Research Centre Nitra, Komenského 73, Košice, Slovak Republic
2
University of Veterinary Medicine, Komenského 73, Košice, Slovak Republic
3
Institute of Animal Physiology, Slovak Academy of Sciences, Šoltésovej 4-6, Košice, Slovak Republic
J. Anim. Feed Sci. 2010;19(3):358–367
Publication date: 2010-08-16
KEYWORDS
ABSTRACT
In order to examine the relation of known intestinal lesions to changes in T-cell phenotypes and integrin expression, 16 male 10-day-old Holstein calves were divided into two groups. For 28 days of the experiment, eight males were fed NutriMilk in which 50% of the crude protein was soya protein, and eight control animals, with NutriMilk containing only milk casein. The animals fed soya protein showed shorter jejunal villi with a corrugated surface and deeper crypts compared with the control calves. A higher density of CD8+ cells in the intestinal mucosa and a decrease of these cells in peripheral blood were found in calves fed soya protein. The number of CD11b-positive cells was decreased in the peripheral blood of calves fed soya protein. Lower expression of integrin could be related to the appearance of non-mature polymorphonuclear cells. It is not clear if the decrease in CD11b expression on blood cells could also be influenced by milk replacer, i.e. soya protein.
CORRESPONDING AUTHOR
R. Žitňan   
Animal Production Research Centre Nitra, Komenského 73, Košice, Slovak Republic
ISSN:1230-1388