ORIGINAL PAPER
Dietary effects of n-6:n-3 polyunsaturated fatty acid ratios on the antioxidant status of the liver in goslings
M. Z. Wang 1  
,   L. Y. Ding 1,   J. F. Wang 1,   L. H. Yu 1,   H. R. Wang 1
 
More details
Hide details
1
College of Animal Science and Technology, Yangzhou University, Yangzhou, Jiangsu province, 225009, P.R. China
CORRESPONDING AUTHOR
M. Z. Wang   

College of Animal Science and Technology, Yangzhou University, Yangzhou, Jiangsu province, 225009, P.R. China
Publication date: 2012-06-19
 
J. Anim. Feed Sci. 2012;21(2):372–382
 
KEYWORDS
ABSTRACT
The objective of this study was to investigate the effects of dietary n-6:n-3 polyunsaturated fatty acid (PUFA) ratios on the oxidative stress of the liver in goslings. A total of 160 healthy Yangzhou geese was randomly divided into 4 groups, and each group was fed on diets with different n-6:n-3 PUFA ratios: A (12:1), B (9:1), C (6:1), and D (3:1), respectively. The liver was separated and antioxidant functions were evaluated on days 42, 56, and 70. The results showed that the activities of total superoxide dismutase, glutathione peroxidase, and catalase decreased when the geese aged, and were highest on d 42 in each group (P<0.05). The activities of these enzymes increased as the n-6:n-3 PUFA ratios decreased and were highest in the 3:1 group at all tested ages (P<0.05). It was also observed that the levels of H2O2, malondialdehyde (MDA), and nitric oxide (NO) in liver tissue tended to increase with age, and were relatively higher on d 70. Furthermore, the levels of H2O2, MDA, and NO decreased as n-6:n-3 PUFA ratios decreased and were lowest at 3:1 and 6:1 at all studied ages (P<0.05). Overall, diets containing comparatively low n-6:n-3 PUFA ratios, such as 3:1 or 6:1, could increase antioxidant function and decrease hepatocyte damage in liver tissue.
 
CITATIONS (5):
1.
Influence of perinatal trans fat on behavioral responses and brain oxidative status of adolescent rats acutely exposed to stress
C.S. Pase, Kr. Roversi, F. Trevizol, K. Roversi, F.T. Kuhn, A.J. Schuster, L.T. Vey, V.T. Dias, R.C.S. Barcelos, J. Piccolo, T. Emanuelli, M.E. Bürger
Neuroscience
 
2.
Effects of dietary n-6/n-3 polyunsaturated fatty acid ratios on the mass, and histological and ultrastructures of liver, spleen and thymus of 70-day-old Yangzhou Goslings
M. Z. Wang, L. Y. Ding, J. Gao, J. F. Wang, G. Zhou, J. Zhang
Journal of Animal Physiology and Animal Nutrition
 
3.
Gamma-oryzanol prevents ethanol-induced liver injury by ameliorating oxidative stress and modulating apoptosis-related protein expression in mice
Lijuan Zhu, Siting Xiang, Zhaoping Ou, Chaoyang Ma, Xianglian Yi, Lin Huang, Yurong Ma, Zengenni Liang, Zhihang Yuan, Lixin Wen, Rongfang Li, Jing Wu, Zhuliang Tan, Jine Yi
Journal of Functional Foods
 
4.
Injury and mechanism of recombinant E. coli expressing STa on piglets colon
Yang LV, Xueni LI, Lin ZHANG, Yutao SHI, Linxiao DU, Binying DING, Yongqing HOU, Joshua GONG, Tao WU
Journal of Veterinary Medical Science
 
5.
Dietary n-9, n-6 and n-3 fatty acids modulate the oxidative stress in brain and liver of mice. Effect of trans fatty acids supplementation
Jimena Lavandera, Verónica Reus, Juliana Saín, Bernal Adrian, Marcela González
Mediterranean Journal of Nutrition and Metabolism
 
ISSN:1230-1388