1.054
IF5
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IF
Q3
JCR
1.7
CiteScore
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SJR
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MNiSW
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ICV
ORIGINAL PAPER
 
CC-BY 4.0
 
 

The molecular mechanism of fat accumulation changes in Black-Bone chickens with different energy intakes

R. L. Qi 1,  
C. Sun 1  ,  
H. L. Yang 1,  
X. Zhao 1,  
Z. Tao 1
 
1
Northwest A & F University, College of Animal Science and Technology, Yangling 712100, P.R. China
J. Anim. Feed Sci. 2012;21(2):361–371
Publication date: 2012-06-19
KEYWORDS
ABSTRACT
To investigate the molecular mechanism by which diets of different energy levels alter fat accumulation, 120 Black-Bone chickens were divided into 3 groups and fed diets with varying energy levels for six weeks (low: 3.02 Mcal/kg, moderate: 3.22 Mcal/kg, high: 3.42 Mcal/kg). The high-energy diet increased the concentration of blood lipids. Furthermore, high-energy intake inhibited the activities of several serum lipases. Histological sections showed over-synthesis of lipids in the livers of chickens fed high-energy diets. Data from western blotting and PCR analyses indicated that key factors for lipogenesis, regulatory transcription factors and fatty acid transporters, were up-regulated, while key factors for lipolysis were down-regulated. Chickens fed low-energy diets showed opposite results. In conclusion, varying energy levels of diets affect fat accumulation in Black-Bone chickens through changed expression of metabolic regulators.
CORRESPONDING AUTHOR
C. Sun   
Northwest A & F University, College of Animal Science and Technology, Yangling 712100, P.R. China
ISSN:1230-1388