0.857
IF5
0.900
IF
Q3
JCR
0.92
CiteScore
0.405
SJR
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SJR
20
MNiSW
165.24
ICV
ORIGINAL PAPER
 
CC-BY 4.0
 
 

Influence of dietary conjugated linoleic acid isomers and selenium on growth, feed efficiency, and liver fatty acid profile in rats

K. Korniluk 1,  
M. Czauderna 1  ,  
J. Kowalczyk 1,  
M. Taciak 1,  
 
1
The Kielanowski Institute of Animal Physiology and Nutrition, Polish Academy of Sciences, 05-110 Jabłonna, Poland
2
Institute of Animal Physiology, Slovak Academy of Sciences, 040 01 Košice, Slovak Republic
J. Anim. Feed Sci. 2006;15(1):131–146
Publish date: 2006-01-06
KEYWORDS
ABSTRACT
The influence of dietary CLA isomer(s) and/or selenized yeast on the growth, concentration of CLA isomers and other fatty acids in the liver was investigated in rats. Plasma blood triacylglycerols (TAG), total cholesterol (TC), HDL and LDL cholesterol fractions in relation to dietary CLA isomer(s) and/or selenium (Se) were analysed. The experiment was performed on female rats (Wistar), 8 weeks of age and initial body weight of about 200 g. After a 1-week preliminary period, for 4 weeks the animals were fed a diet enriched in conjugated linoleic acid (CLA) isomer(s) and selenized yeast (2×2 experimental design). Dietary Se or/and CLA isomer(s) resulted in small changes in the spleen, heart, kidneys and brain, and increased liver weight. Administration of Se and trans10cis12CLA most efficiently increased the body weight gain of rats. CLA isomer(s) administered with or without Se elevated the CLA isomer(s) level in the liver. These results demonstrate that trans,transCLA isomers are metabolized more slowly, while cis,trans/trans,cisCLA isomers, more rapidly to longchain fatty acids containing a conjugated double bond. Enrichment of the diet in CLA isomer(s) with or without Se caused a reduction in the capacity of Δ9-, Δ6- and Δ5-desaturases in the liver, while dietary trans10cis12CLA or the CLA isomer mixture increased Δ4-desaturases. The contents of oleic acid, C20:4n-6, and C20:5n-3 decreased in the liver, whereas the level of C22:5n-3 and C22:6n-3 increased in the liver of rats fed the CLA isomer mixture. Individual dietary CLA isomers with or without Se increased the concentration of palmitic and stearic acids in the liver. All experimental diets increased the concentration of triacylglycerols in blood plasma, while trans10cis12CLA with or without Se usually decreased the concentration of total cholesterol, LDL, and HDL cholesterol.
CORRESPONDING AUTHOR
M. Czauderna   
The Kielanowski Institute of Animal Physiology and Nutrition, Polish Academy of Sciences, 05-110 Jabłonna, Poland
 
CITATIONS (2):
1. Seleno-methionine decreases biohydrogenation of C18 unsaturated fatty acids in ovine ruminal fluid incubated in vitro with α-linolenic acid
Marian Czauderna, Agnieszka J. Rozbicka-Wieczorek, Edyta Więsyk, Katarzyna A. Krajewska-Bienias
European Journal of Lipid Science and Technology
2. Effect of dietary conjugated linoleic acid and selenized yeast on the concentration of fatty acids and minerals in rats
Marian Czauderna, Jan Kowalczyk, Katarzyna Korniluk
Archives of Animal Nutrition
ISSN:1230-1388