1.054
IF5
1.150
IF
Q3
JCR
1.7
CiteScore
0.396
SJR
Q2
SJR
40
MNiSW
148.75
ICV
ORIGINAL PAPER
 
CC-BY 4.0
 
 

Conjugated linoleic acid decreased serum triacyloglycerol and changed fatty acid composition in rat’s liver

R. B. Kostogrys 1  ,  
 
1
Agricultural University of Kraków, Department of Human Nutrition, Faculty of Food Technology, Balicka 122, 30-149 Kraków, Poland
J. Anim. Feed Sci. 2010;19(3):484–494
Publication date: 2010-08-19
KEYWORDS
ABSTRACT
Extensive research have indicated that commercial conjugated linoleic acid (CLA), fed to laboratory animals, showed several health-related properties. The objective of this study was to assess the effect of CLA on serum lipid profile, plasma malondialdehyde and liver fatty profile in Wistar rats fed for 23 d. The experimental diets were: I-AIN-93G - control (C), II- AIN-93G diet + 1.0% CLA. The CLA oil contained 600 g CLA/kg, with equal representation of cis-9,trans-11 and trans-10,cis-12 CLA isomers. The experimental treatments had no effect on rats body weight, total cholesterol, HDL, LDL+VLDL and malondialdehyde. The triacylglycerol (TG) was significantly decreased after CLA supplementation. Liver weight, fat and histology were unchanged in CLA group. Liver cholesterol was insignificantly decreased in CLA diet. Dietary treatments had significant effects of on proportions of SFA and MUFA and PUFA in liver. In conclusion, CLA decreases serum TG. Additionally, liver fat composition were changed after CLA supplementation
CORRESPONDING AUTHOR
R. B. Kostogrys   
Agricultural University of Kraków, Department of Human Nutrition, Faculty of Food Technology, Balicka 122, 30-149 Kraków, Poland
 
CITATIONS (3):
1. Effects of margarine supplemented with T10C12 and C9T11 CLA on atherosclerosis and steatosis in apoE/LDLR -/- mice
Renata B. Kostogrys, M. Franczyk-Żarow, E. Maslak, M. Gajda, Ł. Mateuszuk, S. Chłopicki
The journal of nutrition, health & aging
2. Margarine supplemented with conjugated linolenic acid (CLnA) has no effect on atherosclerosis but alleviates the liver steatosis and affects the expression of lipid metabolism genes in apoE/LDLR-/-mice
Magdalena Franczyk-Żarów, Izabela Czyżyńska, Anna Drahun, Edyta Maślak, Stefan Chłopicki, Renata B. Kostogrys
European Journal of Lipid Science and Technology
3. Liver and serum lipids in Wistar rats fed a novel structured lipid containing conjugated linoleic acid and conjugated linolenic acid
M. Shagholian, S. A.H. Goli, A. Shirvani, M. R. Agha-Ghazvini, S. Asgary
Grasas y Aceites
ISSN:1230-1388