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ORIGINAL PAPER
Effects of gamma-aminobutyric acid alone and in combination
with coated sodium butyrate on growth performance, meat quality
and nutrient utilisation in heat-stressed broiler chickens
1
Zhumadian Huazhong Chia Tai Co., Ltd, Jianshe Road No.6, High Technology Development Zone,
Zhumadian City, Henan Province, 460000, P.R China
2
Animal Research and Consultant Co., Ltd (ARC), NKP research farm, Nikompatthna District, Rayong Province, Thailand
3
Tropical Agriculture Innovation and Technology Center (TRAINTEC), Department of Animal Science, Faculty of Agriculture Innovation, Rajamangala University of Technology Isan,
Nakhon Ratchasima Campus, Muang, Nakhon Ratchasima Province, Thailand
4
Department of Animal Science, Faculty of Agriculture, Khon Kaen University, Khon Kaen 40002, Thailand
Publication date: 2026-03-25
Corresponding author
N. Nukitrangsan
Zhumadian Huazhong Chia Tai Co., Ltd, Jianshe Road No.6, High Technology Development Zone, Zhumadian City, Henan Province, 460000, P.R China
Zhumadian Huazhong Chia Tai Co., Ltd, Jianshe Road No.6, High Technology Development Zone, Zhumadian City, Henan Province, 460000, P.R China
KEYWORDS
TOPICS
ABSTRACT
This study investigated the effects of gamma-aminobutyric acid
(GABA) and its combination with coated sodium butyrate (CSB) on growth
performance, meat quality, and nutrient utilisation in heat-stressed broilers. In
Trait 1, 90 newly hatched male Ross 308 broilers were randomly allocated to
3 dietary treatments for 42 days: a positive control diet (PC), PC + 0.05% (20%
GABA), and PC + 0.03% (20% GABA) + 0.05% (50% CSB). In Trait 2, 120 birds
were divided into 4 dietary treatment groups for 24–28 days: PC, a negative
control (NC), formulated by reducing PC metabolizable energy by 100 kcal/kg,
NC + 0.05% (20% GABA), and NC + 0.03% (20% GABA) + 0.05% (50% CSB).
All groups were exposed to chronic heat stress in a closed house and acute
heat stress during transportation. In Trait 1, GABA or its combination with CSB
improved feed conversion ratio, European production efficiency index, posttransport
body weight, heterophil-to-lymphocyte ratio, and thiobarbituric acid
reactive substances (P < 0.05). In Trait 2, GABA or its combination with CSB
increased apparent metabolisable energy, and nitrogen-corrected metabolizable
energy (P < 0.01) compared to the NC. In conclusion, the GABA + CSB
combination resulted in the highest improvement in growth performance and
meat quality. GABA and its combination with CSB also increased the energy
matrix value of broiler feed.
CONFLICT OF INTEREST
The Authors declare that there is no conflict of interest.
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