1.054
IF5
1.150
IF
Q3
JCR
1.7
CiteScore
0.396
SJR
Q2
SJR
40
MNiSW
148.75
ICV
ORIGINAL PAPER
 
CC-BY 4.0
 
 

The effects of selenium and conjugated linoleic acid (CLA) isomers on fatty acid composition, CLA isomer content in tissues, and growth of rats

M. Czauderna 1  ,  
J. Kowalczyk 1,  
I. Wąsowska 1,  
 
1
The Kielanowski Institute of Animal Physiology and Nutrition, Polish Academy of Sciences, 05-110 Jabłonna, Poland
J. Anim. Feed Sci. 2003;12(4):865–881
Publication date: 2003-10-28
KEYWORDS
ABSTRACT
The effects of conjugated linoleic acid (CLA) isomers and/or selenium (as Na2SeO4) on rat growth performance and levels of some fatty acids (FA) in femoral muscles and perigonadal fat were investigated. Feeding a mixture of CLA isomers, the trans-10,cis-12 isomer, or selenium (Se) tended to decrease the rats’ body weight compared with the control animals, whereas a diet supplemented with both Se and the trans-10,cis-12 isomer produced the highest increase in body weight gain and the highest feed conversion efficiency. None of the experimental diets had any influence on brain, kidney, pancreas, or liver weight, while they significantly increased spleen mass. The administered CLA isomers significantly increased the contents of CLA isomers and non-CLA fatty acids containing conjugated double bonds (CD) in the assayed tissues. Se and individual CLA isomers or their mixture increased the CLA isomer and CD contents in muscles, while feeding only the cis-9, trans-11 isomer and Se resulted in an increase in CD and sum of all CLA isomers in fat. These results demonstrate that the trans-10,cis-12 isomer is preferentially driven through the β-oxidation pathway in muscles and fat compared with the cis-9,trans-11 isomer. CLA isomers added to Se-unsupplemented or -supplemented diets increased the levels of total FA in muscles only, while decreased the level of total assayed saturated FA in fat. Feeding Se and individual CLAs or a mixture of these isomers resulted in increasing both the sum of cis-monounsaturated FA (cis-MUFA), CD and polyunsaturated FA (PUFA) in muscles, but generally resulted in decreasing the level of total saturated FA, cis-MUFA and PUFA in fat. The interaction between Se and a mixture of CLA isomers or the trans-10,cis-12 isomer most effectively protected CLA isomers from peroxidation damage and/or catabolism in muscles.
CORRESPONDING AUTHOR
M. Czauderna   
The Kielanowski Institute of Animal Physiology and Nutrition, Polish Academy of Sciences, 05-110 Jabłonna, Poland
 
CITATIONS (6):
1. Performance and tissue fatty acid profiles in veal calves fed diets supplemented with conjugated linoleic acids
Milan Marounek, Věra Skřivanová, Alena Výborná, Dagmar Dušková
Archives of Animal Nutrition
2. Protein and energy metabolism of young male Wistar rats fed conjugated linoleic acid as structured triacylglycerol
Henry Jørgensen, Christina Hørup Hansen, Huiling Mu †, Kirsten Jakobsen
Archives of Animal Nutrition
3. Effect of dietary conjugated linoleic acid and selenized yeast on the concentration of fatty acids and minerals in rats
Marian Czauderna, Jan Kowalczyk, Katarzyna Korniluk
Archives of Animal Nutrition
4. Dietary carnosic acid, selenized yeast, selenate and fish oil affected the concentration of fatty acids, tocopherols, cholesterol and aldehydes in the brains of lambs
Agnieszka J. Rozbicka-Wieczorek, Katarzyna A. Krajewska-Bienias, Marian Czauderna
Archives Animal Breeding
5. Conjugated Linoleic Acid Isomers Affect Profile of Lipid Compounds and Intensity of Their Oxidation in Heart of Rats with Chemically-Induced Mammary Tumors—Preliminary Study
Małgorzata Białek, Agnieszka Białek, Marian Czauderna
Nutrients
6. Maternal and Early Postnatal Diet Supplemented with Conjugated Linoleic Acid Isomers Affect Lipid Profile in Hearts of Offspring Rats with Mammary Tumors
Małgorzata Białek, Agnieszka Białek, Marian Czauderna
Animals
ISSN:1230-1388