ORIGINAL PAPER
Polymorphism of intronic microsatellites in the
A-FABP and LEPR genes and its association with
productive traits in the pig
| 1 | Department of Animal Genetics and Breeding, August Cieszkowski Agricultural University,
Wołyńska 33, Poznań 60-637, Poland |
| 2 | Experimental Station,
60-637 Pawłowice, Poland |
| 3 | National Research Institute of Animal Production,
32-083 Balice, Poland |
CORRESPONDING AUTHOR
M. Świtoński
Department of Animal Genetics and Breeding, August Cieszkowski Agricultural University, Wołyńska 33, Poznań 60-637, Poland
Department of Animal Genetics and Breeding, August Cieszkowski Agricultural University, Wołyńska 33, Poznań 60-637, Poland
Publication date: 2004-10-25
J. Anim. Feed Sci. 2004;13(4):615–624
KEYWORDS
ABSTRACT
The adipocyte fatty acid-binding protein (A-FABP) and leptin receptor (LEPR) genes are
candidate quantitative trait loci (QTLs) for fatness traits in the pig. In both genes polymorphic short
tandem repeat (STR) sequences in intron 1 (A-FABP) and in intron 3 (LEPR) were revealed. The
association studies between both polymorphisms and productive traits were performed in two breeds
(Polish Large White and Polish Landrace) and one synthetic line (L990) of the pig. In the A-FABP
ten and in the LEPR gene eight alleles were identified, and the polymorphic information content
(PIC) values ranged from 0.713 to 0.749 and from 0.441 to 0.557, respectively. The associations
with backfat thickness and intramuscular fat content were found. Since the observed relationships
considering each gene were not concordant in all the studied populations, it was concluded that both
genes are linked with an unknown QTL.
CITATIONS (10):
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Molecular Biology Reports
2.
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Cristina Óvilo, Almudena Fernández, Ana I. Fernández, Josep M. Folch, Luis Varona, Rita Benítez, Yolanda Nuñez, Carmen Rodríguez, Luis Silió
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Cristina Óvilo, Almudena Fernández, Ana I. Fernández, Josep M. Folch, Luis Varona, Rita Benítez, Yolanda Nuñez, Carmen Rodríguez, Luis Silió
Mammalian Genome
3.
A splice site single nucleotide polymorphism of thefatty acid binding protein 4gene appears to be associated with intramuscular fat deposition in longissimus muscle in Australian cattle
W. Barendse, R. J. Bunch, M. B. Thomas, B. E. Harrison
Animal Genetics
W. Barendse, R. J. Bunch, M. B. Thomas, B. E. Harrison
Animal Genetics
4.
The multigene family of fatty acid-binding proteins (FABPs): Function, structure and polymorphism
Agata Chmurzyńska
Journal of Applied Genetics
Agata Chmurzyńska
Journal of Applied Genetics
5.
Genetics of fat tissue accumulation in pigs: a comparative approach
M. Switonski, M. Stachowiak, J. Cieslak, M. Bartz, M. Grzes
Journal of Applied Genetics
M. Switonski, M. Stachowiak, J. Cieslak, M. Bartz, M. Grzes
Journal of Applied Genetics
6.
Missense mutations in exon 4 of the porcine LEPR gene encoding extracellular domain and their association with fatness traits
M. Mackowski, K. Szymoniak, M. Szydlowski, M. Kamyczek, R. Eckert, M. Rozycki, M. Switonski
Animal Genetics
M. Mackowski, K. Szymoniak, M. Szydlowski, M. Kamyczek, R. Eckert, M. Rozycki, M. Switonski
Animal Genetics
8.
Genetic Polymorphism of Microsatellite Loci and Their Association with Reproductive Traits in Ukrainian Meat Breed Pigs
S. I. Lugovoy, V. R. Kharzinova, S. S. Kramarenko, A. V. Lykhach, A. S. Kramarenko, V. Ya. Lykhach
Cytology and Genetics
S. I. Lugovoy, V. R. Kharzinova, S. S. Kramarenko, A. V. Lykhach, A. S. Kramarenko, V. Ya. Lykhach
Cytology and Genetics
9.
Intra- and interbreed genetic heterogeneity and divergence in four commercial pig breeds based on microsatellite markers
E. Snegin, A. Kramarenko, O. Artemchuk, S. Kramarenko
Regulatory Mechanisms in Biosystems
E. Snegin, A. Kramarenko, O. Artemchuk, S. Kramarenko
Regulatory Mechanisms in Biosystems
10.
Polymorphism of Selected Microsatellite Markers against Breeding Performance Indexes of Polish Large White and Polish Landrace Sows
Błażej Nowak, Anna Mucha, Magdalena Moska, Magdalena Zatoń-Dobrowolska, Wojciech Kruszyński
Agriculture
Błażej Nowak, Anna Mucha, Magdalena Moska, Magdalena Zatoń-Dobrowolska, Wojciech Kruszyński
Agriculture
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