0.917
IF5
1.024
IF
Q2
JCR
0.90
CiteScore
0.385
SJR
Q2
SJR
20
MNiSW
142.18
ICV
Submit your paper
Instructions for Authors Archive
2/2017 vol. 26
PREVIOUS NEXT
ORIGINAL PAPER
 
CC-BY 4.0
 
 

Impacts of restricted feeding and realimentation on bone development and plasma concentrations of bone-specific biomarkers in lambs

A. A. Swelum 1, 2  ,  
I. M. Saadeldin 1, 3,  
A. N. Alowaimer 1,  
A. Mahmoud 4,  
M. A. Abouheif 1
 
1
King Saud University, College of Food and Agriculture Sciences, Department of Animal Production, Riyadh 11451, Saudi Arabia
2
Zagazig University, Faculty of Veterinary Medicine, Department of Theriogenology, Zagazig 44519, Egypt
3
Zagazig University, Faculty of Veterinary Medicine, Department of Physiology, Zagazig 44519, Egypt
4
King Saud University, College of Science, Department of Zoology, Riyadh 11451, Saudi Arabia
J. Anim. Feed Sci. 2017;26(2):116–122
Publish date: 2017-06-02
DOI: https://doi.org/10.22358/jafs/74008/2017
Stats Article (PDF)
Get citation
References (19)
 
KEYWORDS:
feed restriction, bone length, phosphorus, osteocalcin, lambs
ABSTRACT:
The aim of the study was to assess the effect of feed restriction levels followed by realimentation on long bone growth and concentrations of growth hormone, osteocalcin, bone-specific alkaline phosphatase (ALP), calcium (Ca) and phosphorus (P) in plasma. Thirty-six Najdi ram lambs weighing 30.1 ± 0.3 kg were randomly allotted to one of three feeding regimens. The first group was fed ad libitum throughout the trial (AD group). Other groups were subjected to 5-week feed restriction at either 0.75 or 0.60 of ad libitum intake (0.75AD and 0.60AD groups, respectively). Following the restriction period, lambs were returned to ad libitum feeding (realimentation) for 7 weeks. Feed restriction suppressed (P < 0.01) the growth of bone lengths in proportion to the restriction level. After the realimentation, bone lengths of animals from either 0.75AD or 0.60AD groups did not recover to the lengths of AD group. Plasma concentrations of inorganic P and osteocalcin decreased (P < 0.01) as the level of feed restriction increased. Concentration of plasma bone-specific ALP increased (P < 0.01) by 39.6 and 72.7% in 0.75AD and 0.60AD groups, respectively. After 4 weeks of realimentation, plasma concentrations of osteocalcin, ALP and P did not differ between all groups. The ulna, humerus and femur linear lengths were directly correlated with the level of osteocalcin and P; however, they showed a negative correlation with the level of ALP. Therefore, plasma concentration of P, osteocalcin and ALP appeared to be suitable bone markers for detecting changes in bone length due to variation in feed restriction levels.
CORRESPONDING AUTHOR:
A. A. Swelum   
King Saud University, College of Food and Agriculture Sciences, Department of Animal Production, Riyadh 11451, Saudi Arabia
 
REFERENCES (19):
1. Abouheif M., Al-Owaimer A., Kraidees M., Metwally H., Shafey T., 2013. Effect of restricted feeding and realimentation on feed performance and carcass characteristics of growing lambs. Rev. Bras. Zootecn. 42, 95–101, http://doi.org/10.1590/S1516-35982013000200003.
2. BelićM., SvetinaA., Kušec V., Rakočević S., Grizelj J., RobićM., Turk R., 2010. Bone alkaline phosphatase, osteocalcin and C-terminal telopeptide as bone turnover markers in canine bitches. Vet. Arh. 80, 705–713.
3. Clemens T.L., Karsenty G., 2011. The osteoblast: an insulin target cell controlling glucose homeostasis. J. Bone Miner. Res. 26, 677– 680, https://doi.org/10.1002/jbmr.321.
4. Dashtizadeh M., Zamiri M.J., Kamalzadeh A., Kamali A., 2008. Effect of feed restriction on compensatory growth response of young male goats. Iran. J. Vet. Res. 9, 109–120.
5. Kang M.-H., Kim M.-H., Bae Y.-J., Choi M.-K., 2010. Vegetable and fruit intake and its relevance with serum osteocalcin and urinary deoxypyridinoline in Korean adults. Nutr. Res. Pract. 4, 421–427, https://doi.org/10.4162/nrp.2010.4.5.421.
6. Louvandini H., Vitti D.M.S., 1996. Phosphorus metabolism and estimation of phosphorus requirements for sheep. Sci. Agric. 53, 184-189, https://doi.org/10.1590/S0103-90161996000100027.
7. MacRae J.C., Bruce L.A., Hovell F.B.DeB., Hart I.C., Inkster J., WalkerA., Atkinson T., 1991. Influence of protein nutrition on the response of growing lambs to exogenous bovine growth hormone. J. Endocrinol. 130, 53–61, https://doi.org/10.1677/joe.0.1300053.
8. Ndiaye B., Prudhon C., Guillozo H., Lemonnier D., 1992. Rat serum osteocalcin concentration is determined by food intake and not by inflammation. J. Nutr. 122, 1870–1874.
9. Nicodemo M.L.F., Scott D., Buchan W., Duncan A., Robins S.P., 1999. Effects of variations in live weight gain on bone growth and composition and on markers of bone turnover in lambs. Exp. Physiol. 84, 579–587, https://doi.org/10.1111/j.1469-445X.1999.01825.x.
10. NRC, 2007. Nutrient Requirements of Small Ruminants: Sheep, Goats, Cervids, and New World Camelids. National Academy Press. Washington, DC (USA), https://doi.org/10.17226/11654.
11. Peralta J.M., Arnold A.M., Currie W.B., Thorney M.L., 1994. Effects of testosterone on skeletal growth in lambs as assessed by labeling index of chondrocytes in the metacarpal bone growth plate. J. Anim. Sci. 72, 2629–2634, https://doi.org/10.2527/1994.72102629x.
12. Peterson A.B., Orth M.W., Goff J.P., Beede D.K., 2005. Periparturient responses of multiparous Holstein cows fed different dietary phosphorus concentrations prepartum. J. Dairy Sci. 88, 3582–3594, https://doi.org/10.3168/jds.S0022-0302(05)73043-5.
13. Portilho F.P., Vitti D.M.S.S., Abdalla A.L., McManus C.M., Rezende M.J.M., Louvandini H., 2006. Minimum phosphorus requirement for Santa Inês lambs reared under tropical conditions. Small Rumin. Res. 63, 170–176, https://doi.org/10.1016/j.smallrumres.2005.03.006.
14. Prentice A., Schoenmakers I., Laskey M.A., de Bono S., Ginty F., Goldberg G.R., 2006. Nutrition and bone growth and development. Proc. Nutr. Soc. 65, 348–360, https://doi.org/10.1079/PNS2006519.
15. Remmers F., Fodor M., Delemarre-van de Waal H.A., 2008. Neonatal food restriction permanently alters rat body dimensions and energy intake. Physiol. Behav. 95, 208–215, https://doi.org/10.1016/j.physbeh.2008.05.021.
16. Sami A., Shafey T., Abouheif M., 2013. Growth rate of carcass, noncarcass and chemical components of restricted fed and realimented growing lambs. Int. J. Agric. Biol. 15, 307–312.
17. SAS, 2002. SAS User’s Guide: Statistics Version. 8th Edition. SAS Inc., Cary, NC (USA).
18. Scott D., Loveridge N., Nicodemo L., Buchan W., Milne J., Duncan A., Nicol P., Robins S.P., 1997. Effect of diets varying in nitrogen or phosphorus content on indicators of bone growth in lambs. Exp. Physiol. 82, 193–202, https://doi.org/10.1113/expphysiol.1997.sp004008.
19. Thompson W.R., 1978. Phosphorus in Animal Nutrition. Phosphorus for Agriculture: A Situation Analysis. Potash and Phosphate Institute, Atlanta, GA (USA), pp. 126–158.
Send by email
Copy url
Share
 
 
Related articles
The effect of Mediterranean thyme (Thymbra spicata L. var. spicata) essential oil on fattening performance and ruminal parameters in lamb
Selenium supplementation into diets containing carnosic acid, fish and rapeseed oils affects the chemical profile of whole blood in lambs
Tissue protein synthesis in lambs infected with Trichostrongylus colubriformis
Leptin concentrations in Jezersko-Solchava lambs and growing rams
Indexes
 
Keywords index
Topics index
Authors index
ISSN:1230-1388
Creating new databases of archival papers in modern technology, assigning DOI numbers, language correction of manuscripts, creating new databases of reviewers, introduction of anti-plagiarism detection and improvement of publishing process of Journal of Animal and Feed Sciences are financed in the years 2016-2017 by the Ministry of Science and Higher Education from the founds for science popularization activities, Contract No. 730/P-DUN/2016.
Copyright © 2006-2017 Bentus All rights reserved.