0.857
IF5
0.900
IF
Q3
JCR
0.92
CiteScore
0.405
SJR
Q2
SJR
20
MNiSW
165.24
ICV
ORIGINAL PAPER
 
CC-BY 4.0
 
 

Effect of caprylic, capric and oleic acid on growth of rumen and rabbit caecal bacteria

M. Marounek 1,  
 
1
Institute of Animal Physiology and Genetics, Czech Academy of Sciences, 104 00, Prague 10, Uhřiněves, Czech Republic
2
Research Institute of Animal Production, 104 01 Prague 10, Uhřiněves, Czech Republic
J. Anim. Feed Sci. 2002;11(3):507–516
Publish date: 2002-08-02
KEYWORDS
ABSTRACT
In a search for alternatives of in-feed antibiotics, the antimicrobial activity of caprylic (C8:0), capric (C10:0) and oleic (C18:1) acid was investigated in pure cultures of 19 strains of rumen and rabbit caecal bacteria, and in incubations of the rumen and rabbit caecal contents. In glucose-grown bacterial cultures the minimum inhibitory concentration (MIC) of caprylic acid ranged from 1 to 3 µl∙ml-1. Two strains of Bacteroides ovatus were less susceptible to capric than to caprylic acid. In other strains, the MIC of capric acid was 0.25-0.50 µl∙ml-1. The growth of most strains was not much affected by oleic acid. An exception to this were rumen bacteria Butyrivibrio fibrisolvens (MIC from < 0.05 to 1 µl∙ml-1) and Lachnospira multiparus ( MIC of 0.25 to 1 µl∙ml-1). In incubations of the rumen and caecal contents caprylic and capric acid decreased the production of volatile fatty acids and gas, and increased production of lactate. In latter incubations the inhibitory effects of caprylic and capric acid were similar. In incubations of the rumen contents, capric acid was more efficient than caprylic acid when supplied at low concentrations (<1.25 µl∙ml-1) , but less efficient when supplied at 2.5 and 5 µl∙ml-1. Effects of oleic acid in rumen and caecal cultures were not significant, except the increase in production of lactate by rumen microorganisms. It can be concluded that microorganisms of the animal digestive tract are susceptible to inhibition by caprylic and capric acid added to microbial cultures at fairly low concentrations. Oleic acid was far less effective.
CORRESPONDING AUTHOR
M. Marounek
Institute of Animal Physiology and Genetics, Czech Academy of Sciences, 104 00, Prague 10, Uhrineves, Czech Republic
 
CITATIONS (10):
1. Leukocytic response and composition of enteral microbiota in chickens fed a sage extract supplemented diet and infected withSalmonellaEnteritidis PT4
V. Spišáková, M. Levkutová, V. Revajová, Z. Ševčíková, A. Lauková, M. Levkut, V. Strompfová, J. Pistl, M. Levkut
Food and Agricultural Immunology
2. Comparative Metabolomic-Based Metabolic Mechanism Hypothesis for Microbial Mixed Cultures Utilizing Cane Molasses Wastewater for Higher 2-Phenylethanol Production
Xinrong Pan, Haishan Qi, Li Mu, Jianping Wen, Xiaoqiang Jia
Journal of Agricultural and Food Chemistry
3. Effects of medium-chain fatty acids on the structure and immune response of IPEC-J2 cells
B. Martínez-Vallespín, W. Vahjen, J. Zentek
Cytotechnology
4. Metabolism of polyunsaturated fatty acids and their toxicity to the microflora of the rumen
Margarida R. G. Maia, Lal C. Chaudhary, Lauren Figueres, R. John Wallace
Antonie van Leeuwenhoek
5. Testing the efficacy of medium chain fatty acids against rabbit colibacillosis
Mélanie Gallois, Thierry Gidenne, Juan Orengo, Cécile Caubet, Christian Tasca, Alain Milon, Séverine Boullier
Veterinary Microbiology
6. Effect of late weaning and use of alternative cages on performance of does, suckling and fattening rabbits under extensive reproductive management
C. Alfonso-Carrillo, P. García-Rebollar, C. De Blas, M.A. Ibáñez, A.I. García-Ruiz
Livestock Science
7. Effects of dietary fish oil supplementation on performance, meat quality, and cecal fermentation of growing rabbits1
M. Rodríguez, M. D. Carro, V. Valiente, N. Formoso-Rafferty, P. G. Rebollar
Journal of Animal Science
8. The application of caprylic acid in downstream processing of monoclonal antibodies
Yifeng Li
Protein Expression and Purification
9. Influence of Dietary Inclusion with Corn and Soybean Oils, in Combination with Live Yeast Culture, on Horse Fecal Methane, Carbon Dioxide and Hydrogen Productions
Alejandro E. Velázquez, Mona M.M.Y. Elghandour, Moyosore J. Adegbeye, Alberto B. Pilego, Laura H. Vallejo, Abdelfattah Z.M. Salem, Moisés C. Salazar
Journal of Equine Veterinary Science
10. Susceptibility ofEscherichia coli to C2-C18 fatty acids
M. Marounek, E. Skřivanová, V. Rada
Folia Microbiologica
ISSN:1230-1388