Effect of 4-MeSer-GnRH on the release
and synthesis of gonadotropins in the female
rat  in vivo

The experiment was performed to confirm selective stimulation of FSH release by GnRH analog 4-MeSer-GnRH and to determine if analog can act on α, LHβ and prolactin gene expression. Our studies in vivo have shown that 4-MeSer-GnRH FSH releasing potency was less expressed than it was shown in our previous experiments and that this peptide did not affect LH release. GnRH analog inhibited both pituitary prolactin and LHβ mRNAs level but this effect was much more strongly expressed in case of prolactin mRNA. Such data point out a necessity of more detailed studies on the biological properties of 4-MeSer-GnRH.

Submit your paper

Instructions for Authors

Archive

Send by email

Effect of caffeine on adenosine and ryanodine receptor gene expression in the hypothalamus, pituitary, and choroid plexus in ewes under basal and LPS challenge conditions

Brain-derived neurotrophic factor (BDNF) affects somatotrophic axis activity in sheep

Effects of opioid and cholinergic receptors inhibition on the intestine hormones concentration and release in rats

The effects of mu-, delta- and kappa-opioid receptor activation on in vitro prolactin secretion by anterior pituitary cells of cyclic gilts

Effects of polyunsaturated fatty acids on hepatic PPARα mRNA levels in the transition cow

Indexes

Keywords index

Topics index

Authors index

ISSN:

1230-1388

Assigning DOI numbers, introducing articles from supplements and recent publications to POL-index database, maintaining anti-plagiarism detection, electronic system to proceed manuscripts and webpage of the Journal with interactive pdf files, and language correction of manuscripts published in Journal of Animal and Feed Sciences are financed in the years 2018–2019 by the Ministry of Science and Higher Education from the funds for science popularization activities, Agreement No. 631/P-DUN/2018.