SHORT COMMUNICATION
Effects of polyunsaturated fatty acids on hepatic
PPARα mRNA levels in the transition cow
1
Dairy and Swine Research and Development Centre, Agriculture and Agri-Food Canada,
Lennoxville, Quebec, Canada J1M 1Z3
Publication date: 2004-08-30
Corresponding author
M. F. Palin
Dairy and Swine Research and Development Centre, Agriculture and Agri-Food Canada, Lennoxville, Quebec, Canada J1M 1Z3
Dairy and Swine Research and Development Centre, Agriculture and Agri-Food Canada, Lennoxville, Quebec, Canada J1M 1Z3
J. Anim. Feed Sci. 2004;13(Suppl. 1):445-448
KEYWORDS
ABSTRACT
A total of 33 Holstein cows were fed one of three diets with different fatty acid composition:
supplement with 85% saturated fatty acids (EB), supplement with 10% linseed (LI), and control with
no added fat (CO). Blood and liver samples were collected on week -6, -2, +2, and +4 relative to
calving. Two weeks after calving, liver PPARα mRNA levels were lower in cows fed EB compared
to those that were fed CO. These results also showed that lower liver PPARα mRNA levels are
associated with lower plasma glucose concentration in the overall cow population (n=33)
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