REVIEW PAPER
Application of nutrigenomics tools in animal
feeding and nutritional research
1 |
Institute of Animal Reproduction and Food Research,
Polish Academy of Sciences,
Tuwima 10, 10-747 Olsztyn, Poland |
2 |
Nicolaus Copernicus University,
Institute of General and Molecular Biology, Faculty of Biology and Earth Sciences,
Laboratory of Functional Genomics,
Gagarina 9, 87-100 Toruń, Poland |
J. Anim. Feed Sci. 2009;18(1):3–16
Publication date: 2009-01-23
KEYWORDS
ABSTRACT
The development of nutrigenomic studies has brought about a number of new research tools
(transcriptomics, proteomics and metabolomics), which are important in animal nutrition and
food research. This review presents an overview on the application of nutrigenomics tools in this
scientific area. The use of microarray technologies - the main tools of transcriptomics, has allowed
new information concerning the physiological effect of different dietary proteins, of omega-3
polyunsaturated fatty acids and dietary conditioning of colon cancer, to be obtained. The use of
proteomics tools (mainly two-dimensional electrophoresis) revealed new information concerning the
protein composition of egg and poultry meat proteins, the effect of dietary methionine on breast-meat
accretion, the toxicity of dioxin and the safe use of transgenic crops in animal nutrition. Metabolomic
analysis allowed the detection of changes in the biochemical profiles of plasma and urine from
pigs fed different diets and the determination of metabolite profiles in the liver of rats used as an
animal model to characterize the toxicity of triazol fungicides. In livestock species, the microarray
technology was discussed and reviewed as potential nutrigenomics tools, in context to its economic
benefi ts and improvement of the food quality and safety in dairy and meat industries. However,
the newly emerged nutrigenomics tools like - gene expression-based biomarker development still
poses a major challenge. Finally, latest developments in the standardization of metobolomics data in
relation to functional genomics, nutrigenomics and toxicology studies are discussed.
CORRESPONDING AUTHOR
Z. Zduńczyk
Institute of Animal Reproduction and Food Research,
Polish Academy of Sciences,
Tuwima 10, 10-747 Olsztyn, Poland
CITATIONS (8):
1. |
Dietary prebiotics and probiotics influence growth performance, nutrient digestibility and the expression of immune regulatory genes in snakehead (Channa striata) fingerlings Mohammad Bodrul Munir, Roshada Hashim, Yam Hok Chai, Terence L. Marsh, Siti Azizah Mohd Nor Aquaculture
|
2. |
Nutrigenomics research: a review V. S. Neeha, Priyamvadah Kinth Journal of Food Science and Technology
|
3. |
Growth performance and expression of immune-regulatory genes in rainbow trout (Oncorhynchus mykiss) juveniles fed extruded diets with varying levels of lupin (Lupinus albus), peas (Pisum sativum) and rapeseed (Brassica napus) A.J. Hernández, D. Román, J. Hooft, C. Cofre, V. Cepeda, R. Vidal Aquaculture Nutrition
|
4. |
A Tool for Sheep Product Quality: Custom Microarrays from Public Databases Silvia Bongiorni, Giovanni Chillemi, Gianluca Prosperini, Susana Bueno, Alessio Valentini, Lorraine Pariset Nutrients
|
5. |
Modulation of cytokine expression by dietary levan in the pathogen aggravated rohu, Labeo rohita fingerlings Sanjay K. Gupta, B. Sarkar, S. Bhattacharjee, Neeraj Kumar, S. Naskar, Kiran Babu Uppuluri Aquaculture
|
6. |
Does broodstock nutritional history affect the response of progeny to different first-feeding diets? A whole-body transcriptomic study of rainbow trout alevins Viviana Lazzarotto, Geneviève Corraze, Laurence Larroquet, David Mazurais, Françoise Médale British Journal of Nutrition
|
7. |
Nutrition influence on sow reproductive performance and conceptuses development and survival: a review about L-arginine supplementation Karine Costa, Daniele Marques, Campos de, Alysson Saraiva, José Guimarães, Simone Guimarães Livestock Science
|
8. |
Inflammatory and stress biomarker response of Aeromonas hydrophila infected rohu, Labeo rohita fingerlings to dietary microbial levan Sanjay Gupta, B. Sarkar, Manisha Priyam, Neeraj Kumar, S. Naskar, Md Foysal, Shailesh Saurabh, T.R. Sharma Aquaculture
|