REVIEW PAPER
Polar overdominance – a putative molecular mechanism and the new examples in mammals
M. Oczkowicz 1  
 
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National Research Institute of Animal Production, Department of Animal Genetics and Breeding, 32-083 Balice, Poland
CORRESPONDING AUTHOR
M. Oczkowicz   

National Research Institute of Animal Production, Department of Animal Genetics and Breeding, 32-083 Balice, Poland
Publication date: 2009-01-23
 
J. Anim. Feed Sci. 2009;18(1):17–27
 
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ABSTRACT
Polar overdominance is closely related to parental imprinting - a phenomenon where only one (maternal or paternal) allele is expressed in the offspring. In contrast to gametic imprinting, polar overdominance is not very well known and only few examples of this phenomenon have been reported in mammals. One of them is the callipyge phenotype in sheep, which appears in the offspring only when the mutated allele comes from the father and the wild allele comes from the mother. In review, latest concepts on the molecular mechanism underlying the callipyge phenotype are presented and the new examples in mammals are discussed.
 
CITATIONS (1):
1.
Frequency of DLK1 c.639C>T polymorphism and the analysis of MEG3/DLK1/PEG11 cluster expression in muscle of swine raised in Poland
M. Oczkowicz, K. Ropka-Molik, K. Piórkowska, M. Różycki, B. Rejduch
Meat Science
 
ISSN:1230-1388