REVIEW PAPER
Relevance of the Fusarium toxins deoxynivalenol
and zearalenone in ruminant nutrition. A review
| 1 | Institute of Animal Nutrition, Federal Agricultural Research Centre (FAL), Braunschweig,
Bundesallee 50, D-38116 Braunschweig, Germany |
CORRESPONDING AUTHOR
K. Seeling
Institute of Animal Nutrition, Federal Agricultural Research Centre (FAL), Braunschweig, Bundesallee 50, D-38116 Braunschweig, Germany
Institute of Animal Nutrition, Federal Agricultural Research Centre (FAL), Braunschweig, Bundesallee 50, D-38116 Braunschweig, Germany
Publication date: 2005-01-31
J. Anim. Feed Sci. 2005;14(1):3–40
KEYWORDS
ABSTRACT
Deoxynivalenol (DON) and zearalenone (ZON) produced by Fusarium species are agriculturally
important mycotoxins of relevance to livestock health. While ZON is known to cause oestrogenic
syndromes in animals, a moderate ingestion of DON is associated with reduced performance and
immune function. Among farm animals, ruminants appear to have a higher tolerance towards the
effects of DON and ZON. As a consequence, feed producers may allocate cereals and roughages
which appear contaminated with Fusarium toxins to ruminants. In combination with enhanced toxin
concentrations during so-called Fusarium years, the possible effects in ruminants cannot be overlooked.
However, only limited and inconsistent literature data are available about the effects of DON and ZON
on ruminants. On the basis of the literature, the kinetics, biotransformation and carry over, as well
as the effects of DON and ZON on ruminants, are reviewed. Furthermore, dosage and duration of
toxin exposure as well as genetic and physiological factors of ruminants which could influence the
variability of the toxin effects are considered and discussed. It is concluded that additional research is
needed to study the effects of DON and ZON on ruminants, especially in lactating dairy cows.
CITATIONS (21):
1.
Effects ofFusariummycotoxins in rations with different concentrate proportions on serum haptoglobin and hepatocellular integrity in lactating dairy cows
A. Kinoshita, C. Keese, A. Beineke, U. Meyer, A. Starke, H. Sauerwein, S. Dänicke, J. Rehage
Journal of Animal Physiology and Animal Nutrition
A. Kinoshita, C. Keese, A. Beineke, U. Meyer, A. Starke, H. Sauerwein, S. Dänicke, J. Rehage
Journal of Animal Physiology and Animal Nutrition
2.
Chemical contaminants in feedlot wastes: Concentrations, effects and attenuation
S.J. Khan, D.J. Roser, C.M. Davies, G.M. Peters, R.M. Stuetz, R. Tucker, N.J. Ashbolt
Environment International
S.J. Khan, D.J. Roser, C.M. Davies, G.M. Peters, R.M. Stuetz, R. Tucker, N.J. Ashbolt
Environment International
3.
Simultaneous determination of zearalenone, deoxynivalenol and their metabolites in bovine urine as biomarkers of exposure
J. Winkler, S. Kersten, H. Valenta, L. Hüther, U. Meyer, U. Engelhardt, S. Dänicke
World Mycotoxin Journal
J. Winkler, S. Kersten, H. Valenta, L. Hüther, U. Meyer, U. Engelhardt, S. Dänicke
World Mycotoxin Journal
4.
Effect of deoxynivalenol on apoptosis, barrier function, and expression levels of genes involved in nutrient transport, mitochondrial biogenesis and function in IPEC-J2 cells
Peng Liao, Meifang Liao, Ling Li, Bie Tan, Yulong Yin
Toxicol. Res.
Peng Liao, Meifang Liao, Ling Li, Bie Tan, Yulong Yin
Toxicol. Res.
5.
Risks for animal health related to the presence of zearalenone and its modified forms in feed
Helle‐Katrine Knutsen, Jan Alexander, Lars Barregård, Margherita Bignami, Beat Brüschweiler, Sandra Ceccatelli, Bruce Cottrill, Michael Dinovi, Lutz Edler, Bettina Grasl‐Kraupp, Christer Hogstrand, Laurentius (Ron) Hoogenboom, Carlo Stefano Nebbia, Annette Petersen, Martin Rose, Alain‐Claude Roudot, Tanja Schwerdtle, Christiane Vleminckx, Günter Vollmer, Heather Wallace, Chiara Dall'Asta, Sven Dänicke, Gunnar‐Sundstøl Eriksen, Andrea Altieri, Ruth Roldán‐Torres, Isabelle P Oswald
EFSA Journal
Helle‐Katrine Knutsen, Jan Alexander, Lars Barregård, Margherita Bignami, Beat Brüschweiler, Sandra Ceccatelli, Bruce Cottrill, Michael Dinovi, Lutz Edler, Bettina Grasl‐Kraupp, Christer Hogstrand, Laurentius (Ron) Hoogenboom, Carlo Stefano Nebbia, Annette Petersen, Martin Rose, Alain‐Claude Roudot, Tanja Schwerdtle, Christiane Vleminckx, Günter Vollmer, Heather Wallace, Chiara Dall'Asta, Sven Dänicke, Gunnar‐Sundstøl Eriksen, Andrea Altieri, Ruth Roldán‐Torres, Isabelle P Oswald
EFSA Journal
6.
On the effects of the concentrate proportion of dairy cow rations in the presence and absence of aFusariumtoxin-contaminated triticale on cow performance
Christina Keese, Ulrich Meyer, Jürgen Rehage, Joachim Spilke, Jeannette Boguhn, Gerhard Breves, Sven Dänicke
Archives of Animal Nutrition
Christina Keese, Ulrich Meyer, Jürgen Rehage, Joachim Spilke, Jeannette Boguhn, Gerhard Breves, Sven Dänicke
Archives of Animal Nutrition
7.
Nutritive Value and Mycotoxin Contamination of Herbage in Mountain Locality Exposed to Renewed Cattle Grazing
Marie Štýbnarová, Ludmila Křížová, Stanislav Pavlok, Pavlína Mičová, Oldřich Látal, Jan Pozdíšek
Acta Universitatis Agriculturae et Silviculturae Mendelianae Brunensis
Marie Štýbnarová, Ludmila Křížová, Stanislav Pavlok, Pavlína Mičová, Oldřich Látal, Jan Pozdíšek
Acta Universitatis Agriculturae et Silviculturae Mendelianae Brunensis
8.
Effect of Fusarium toxin-contaminated triticale and forage-to-concentrate ratio on fermentation and microbial protein synthesis in the rumen
B. Hildebrand, J. Boguhn, S. Dänicke, M. Rodehutscord
Journal of Animal Physiology and Animal Nutrition
B. Hildebrand, J. Boguhn, S. Dänicke, M. Rodehutscord
Journal of Animal Physiology and Animal Nutrition
9.
Zearalenone (ZEN) metabolism and residue concentrations in physiological specimens of dairy cows exposed long-term to ZEN-contaminated diets differing in concentrate feed proportions
Sven Dänicke, Christina Keese, Ulrich Meyer, Alexander Starke, Asako Kinoshita, Jürgen Rehage
Archives of Animal Nutrition
Sven Dänicke, Christina Keese, Ulrich Meyer, Alexander Starke, Asako Kinoshita, Jürgen Rehage
Archives of Animal Nutrition
10.
Advances, challenges and opportunities for point-of-need screening of mycotoxins in foods and feeds
Ruben R. G. Soares, Alessandra Ricelli, Corrado Fanelli, Domenico Caputo, Giampiero de Cesare, Virginia Chu, M. Raquel Aires-Barros, João P. Conde
The Analyst
Ruben R. G. Soares, Alessandra Ricelli, Corrado Fanelli, Domenico Caputo, Giampiero de Cesare, Virginia Chu, M. Raquel Aires-Barros, João P. Conde
The Analyst
11.
The efficiency of lactic acid bacteria against pathogenic fungi and mycotoxins
Adam Perczak, Piotr Goliński, Marcin Bryła, Agnieszka Waśkiewicz
Archives of Industrial Hygiene and Toxicology
Adam Perczak, Piotr Goliński, Marcin Bryła, Agnieszka Waśkiewicz
Archives of Industrial Hygiene and Toxicology
12.
Effects and biotransformation of the mycotoxin deoxynivalenol in growing pigs fed with naturally contaminated pelleted grains with and without the addition of Coriobacteriaceum DSM 11798
Amin Sayyari, Christiane Kruse Fæste, Ulrik Hansen, Silvio Uhlig, Tore Framstad, Dian Schatzmayr, Tore Sivertsen
Food Additives & Contaminants: Part A
Amin Sayyari, Christiane Kruse Fæste, Ulrik Hansen, Silvio Uhlig, Tore Framstad, Dian Schatzmayr, Tore Sivertsen
Food Additives & Contaminants: Part A
13.
Binding of Fusarium mycotoxins by fermentative bacteria in vitro
V. Niderkorn, H. Boudra, D.P. Morgavi
Journal of Applied Microbiology
V. Niderkorn, H. Boudra, D.P. Morgavi
Journal of Applied Microbiology
14.
Diversity responses of rumen microbial communities to Fusarium-contaminated feed, evaluated with rumen simulating technology
Egbert Strobel, Karen Seeling, Christoph C. Tebbe
Environmental Microbiology
Egbert Strobel, Karen Seeling, Christoph C. Tebbe
Environmental Microbiology
15.
On the effects ofFusariumtoxin-contaminated wheat and the feed intake level on the metabolism and carry over of zearalenone in dairy cows
K. Seeling, S. Dänicke, K. H. Ueberschär, P. Lebzien, G. Flachowsky
Food Additives and Contaminants
K. Seeling, S. Dänicke, K. H. Ueberschär, P. Lebzien, G. Flachowsky
Food Additives and Contaminants
16.
Effects ofFusariumtoxin-contaminated wheat and feed intake level on the biotransformation and carry-over of deoxynivalenol in dairy cows
K. Seeling, S. Dänicke, H. Valenta, Egmond Van, R. Schothorst, A. Jekel, P. Lebzien, M. Schollenberger, E. Razzazi-Fazeli, G. Flachowsky
Food Additives and Contaminants
K. Seeling, S. Dänicke, H. Valenta, Egmond Van, R. Schothorst, A. Jekel, P. Lebzien, M. Schollenberger, E. Razzazi-Fazeli, G. Flachowsky
Food Additives and Contaminants
17.
Screening of fermentative bacteria for their ability to bind and biotransform deoxynivalenol, zearalenone and fumonisins in anin vitrosimulated corn silage model
V. Niderkorn, D. Morgavi, E. Pujos, A. Tissandier, H. Boudra
Food Additives and Contaminants
V. Niderkorn, D. Morgavi, E. Pujos, A. Tissandier, H. Boudra
Food Additives and Contaminants
18.
Reviews of Environmental Contamination and Toxicology Volume 228
Ksenija Nesic, Snezana Ivanovic, Vladimir Nesic
Ksenija Nesic, Snezana Ivanovic, Vladimir Nesic
19.
Effects of concentrate proportion in the diet with or withoutFusariumtoxin-contaminated triticale on ruminal fermentation and the structural diversity of rumen microbial communitiesin vitro
Jeannette Boguhn, Dominik Neumann, André Helm, Egbert Strobel, Christoph Tebbe, Sven Dänicke, Markus Rodehutscord
Archives of Animal Nutrition
Jeannette Boguhn, Dominik Neumann, André Helm, Egbert Strobel, Christoph Tebbe, Sven Dänicke, Markus Rodehutscord
Archives of Animal Nutrition
20.
The Fusarium toxins deoxynivalenol (DON) and zearalenone (ZON) in animal feeding
Susanne Döll, Sven Dänicke
Preventive Veterinary Medicine
Susanne Döll, Sven Dänicke
Preventive Veterinary Medicine
21.
The Mycotoxin Deoxynivalenol Significantly Alters the Function and Metabolism of Bovine Kidney Epithelial Cells In Vitro
Bailey, Breton, Panic, Cogan, Bailey, Swann, Lee
Toxins
Bailey, Breton, Panic, Cogan, Bailey, Swann, Lee
Toxins
RELATED ARTICLE
Assigning DOI numbers, introducing articles from supplements and recent publications to POL-index database, maintaining anti-plagiarism detection, electronic system to proceed manuscripts and webpage of the Journal with interactive pdf files, and language correction of manuscripts published in Journal of Animal and Feed Sciences are financed in the years 2018–2019 by the Ministry of Science and Higher Education from the funds for science popularization activities, Agreement No. 631/P-DUN/2018.
We process personal data collected when visiting the website. The function of obtaining information about users and their behavior is carried out by voluntarily entered information in forms and saving cookies in end devices. Data, including cookies, are used to provide services, improve the user experience and to analyze the traffic in accordance with the Privacy policy. Data are also collected and processed by Google Analytics tool (more).
You can change cookies settings in your browser. Restricted use of cookies in the browser configuration may affect some functionalities of the website.
You can change cookies settings in your browser. Restricted use of cookies in the browser configuration may affect some functionalities of the website.