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ORIGINAL PAPER
Association between polymorphisms in the STAT5A and GH genes
and beef cattle productivity parameters
1
Lithuanian University of Health Sciences, Institute of Biology Systems and Genetic Research, Faculty of Animal Sciences, Kaunas, Lithuania
2
Lithuanian University of Health Sciences, Department of Physics, Mathematics and Biophysics, Faculty of Medicine, Kaunas, Lithuania
Publication date: 2026-02-23
Corresponding author
N. Pečiulaitienė
Lithuanian University of Health Sciences, Institute of Biology Systems and Genetic Research, Faculty of Animal Sciences, Kaunas, Lithuania
Lithuanian University of Health Sciences, Institute of Biology Systems and Genetic Research, Faculty of Animal Sciences, Kaunas, Lithuania
KEYWORDS
TOPICS
ABSTRACT
The study analysed single nucleotide polymorphisms (SNP) of
the growth hormone (GH) (GH1-exon 5, 2141C>G, GH2-exon 5, 2291A>C,
GH3-intron 3, 1548C>T) and signal transducer and activator of transcription
5A (STAT5A) (exon 7, 6853C>T) in three beef cattle breeds (Angus, Charolais,
and Limousin; n = 124), and their association with productivity traits. Significant
associations were identified between the GH1 (2141C>G) polymorphism and
traits like daily weight gain and carcass weight, with the CC genotype showing the
most favourable effect. The AA genotype of the GH2 (2291A>C) polymorphism
and the CC genotype of the GH3 (1548C>T) polymorphism were the most
common and were associated with higher weight gain and improved carcass
characteristics. For the STAT5 gene, the CC genotype also demonstrated
a significant positive association with productivity traits. These findings highlight
the potential utility of these polymorphisms as genetic markers for beef cattle
selection. This study is the first to report on the frequency of these alleles and
their associations with productivity traits in beef cattle raised in Lithuania.
CONFLICT OF INTEREST
The Authors declare that there is no conflict of
interest.
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