ORIGINAL PAPER
Effects of deoxynivalenol and degradation enzyme
on growth performance and immune responses in
mule ducks
1 |
Department of Animal Science, National I-Lan University,
#1, Sheng-Lung Rd., I-Lan 260, Taiwan |
2 |
Department of Veterinary Medicine, National Chai-Yi University,
Chai-Yi, Taiwan |
3 |
Division of Applied Biology, Animal Technology Institute Taiwan,
Miaoli, Taiwan |
4 |
Department of Animal Science, National Taiwan University,
Taipei, Taiwan |
J. Anim. Feed Sci. 2004;13(2):275–287
Publication date: 2004-04-09
KEYWORDS
ABSTRACT
Effects of deoxynivalenol (DON) on growth performance and immune responses, and the efficiency of DON degradation enzyme (DDE) in mule ducks were investigated. A total of 140 mule
ducklings was equally assigned to treatment groups of control (no DON, no DDE), toxin 1 (5 ppm
DON, no DDE), toxin 2 (10 ppm DON, no DDE), trial 1 (5 ppm DON, 1.5 kg/ton DDE), trial 2 (5
ppm DON, 2.5 kg/ton DDE), trial 3 (10 ppm DON, 1.5 kg/ton DDE), and trial 4 (10 ppm DON, 2.5
kg/ton DDE). There were no significant differences in total feed intake, body weight gain, and feed
efficiency among treatment groups. However, the 5 ppm DON alone, 5 ppm +1.5 kg/ton DDE, and
10 ppm +1.5 kg/ton DDE groups resulted in a significant higher heart, liver and pancreas weight
than those of control group. Pathological lesions in visceral organ and blood biochemistry parameters alteration were observed in mule ducks of all the DON treatment groups. DON challenge also
decreased number of macrophages harvesting from each duck, and a slight improvement could even
be seen if DDE 2.5 kg/ton were added, as compared with control group. These results suggest that
DON exhibited multiple-toxic characteristics, in terms of hepatotoxicity, cardiotoxicity, and immunotoxicity in ducks. The addition of DDE at 1.5 or 2.5 kg/ton in diet have revealed a toxic-sparing
effects in blood biochemistry parameters and immune functions.
CORRESPONDING AUTHOR
Y. H. Cheng
Department of Animal Science, National I-Lan University,
#1, Sheng-Lung Rd., I-Lan 260, Taiwan
CITATIONS (4):
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