ORIGINAL PAPER
Effects of deoxynivalenol and degradation enzyme on growth performance and immune responses in mule ducks
Y. H. Cheng 1  
,   M. H. Chang 2,   Y. A. Lin 1,   J. F. Wu 3,   B. J. Chen 4
 
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1
Department of Animal Science, National I-Lan University, #1, Sheng-Lung Rd., I-Lan 260, Taiwan
2
Department of Veterinary Medicine, National Chai-Yi University, Chai-Yi, Taiwan
3
Division of Applied Biology, Animal Technology Institute Taiwan, Miaoli, Taiwan
4
Department of Animal Science, National Taiwan University, Taipei, Taiwan
CORRESPONDING AUTHOR
Y. H. Cheng   

Department of Animal Science, National I-Lan University, #1, Sheng-Lung Rd., I-Lan 260, Taiwan
Publication date: 2004-04-09
 
J. Anim. Feed Sci. 2004;13(2):275–287
 
KEYWORDS
ABSTRACT
Effects of deoxynivalenol (DON) on growth performance and immune responses, and the efficiency of DON degradation enzyme (DDE) in mule ducks were investigated. A total of 140 mule ducklings was equally assigned to treatment groups of control (no DON, no DDE), toxin 1 (5 ppm DON, no DDE), toxin 2 (10 ppm DON, no DDE), trial 1 (5 ppm DON, 1.5 kg/ton DDE), trial 2 (5 ppm DON, 2.5 kg/ton DDE), trial 3 (10 ppm DON, 1.5 kg/ton DDE), and trial 4 (10 ppm DON, 2.5 kg/ton DDE). There were no significant differences in total feed intake, body weight gain, and feed efficiency among treatment groups. However, the 5 ppm DON alone, 5 ppm +1.5 kg/ton DDE, and 10 ppm +1.5 kg/ton DDE groups resulted in a significant higher heart, liver and pancreas weight than those of control group. Pathological lesions in visceral organ and blood biochemistry parameters alteration were observed in mule ducks of all the DON treatment groups. DON challenge also decreased number of macrophages harvesting from each duck, and a slight improvement could even be seen if DDE 2.5 kg/ton were added, as compared with control group. These results suggest that DON exhibited multiple-toxic characteristics, in terms of hepatotoxicity, cardiotoxicity, and immunotoxicity in ducks. The addition of DDE at 1.5 or 2.5 kg/ton in diet have revealed a toxic-sparing effects in blood biochemistry parameters and immune functions.
 
CITATIONS (5):
1.
The toxicity of Fusarium mycotoxin deoxynivalenol in poultry feeding
W.A. AWAD, K. GHAREEB, J. BÖHM
World's Poultry Science Journal
 
2.
The Toxicological Impacts of the Fusarium Mycotoxin, Deoxynivalenol, in Poultry Flocks with Special Reference to Immunotoxicity
Wageha Awad, Khaled Ghareeb, Josef Böhm, Jürgen Zentek
Toxins
 
3.
An impact of Deoxynivalenol produced by Fusarium graminearum on broiler chickens
Y.-H. Yu, F. S.-H. Hsiao, W. S. Proskura, A. Dybus, Y.-H. Siao, Y.-H. Cheng
Journal of Animal Physiology and Animal Nutrition
 
4.
Microfluidic Assembly Synthesis of Magnetic TiO2@SiO2 Hybrid Photonic Crystal Microspheres for Photocatalytic Degradation of Deoxynivalenol
Qianjin Li, Yang Deng, Shijie Dai, Yuxiang Wu, Wei Li, Siqi Zhuo, Saisai Jiao, Siwei Wang, Yu Jin, Jianlin Li
Journal of Inorganic and Organometallic Polymers and Materials
 
5.
The Effects of Deoxynivalenol (DON) on the Gut Microbiota, Morphology and Immune System of Chicken – A Review
Harry Aguzey, Zhenhua Gao, Wu Haohao, Cheng Guilan, Wu Zhengmin, Chen Junhong
Annals of Animal Science
 
ISSN:1230-1388