Pinus koraiensis seed oil (PinnoThinTM) supplementation reduces body weight gain and lipid concentration in liver and plasma of mice
More details
Hide details
Department of Biological and Environmental Sciences and Technologies, University of Salento, Lecce, Via Prov.le Lecce-Monteroni, I-73100 Lecce, Italy
Lipid Nutrition BV, PO Box 4, 1520 AA Wormerveer, The Netherlands
Publication date: 2008-10-27
Corresponding author
V. Zara   

Department of Biological and Environmental Sciences and Technologies, University of Salento, Lecce, Via Prov.le Lecce-Monteroni, I-73100 Lecce, Italy
J. Anim. Feed Sci. 2008;17(4):621-630
Pinus koraiensis seed oil (pine nut oil), containing pinolenic acid, has been proposed as a beneficial fat by virtue of its effects on some lipid variables. In this study the effects of a pine nut oil-supplemented diet in mice, in comparison to control animals fed with a maize oil enriched diet, were investigated. Pine nut oil caused a significant reduction in body weight gain and liver weight (37.4 and 13.7%, respectively). An impressive decrease in plasma triglycerides and total cholesterol (31.8 and 28.5%, respectively) was also found in pine nut oil-fed animals. Liver lipids were also positively influenced by pine nut oil. The mitochondrial and cytosolic enzyme activities involved in hepatic fatty acid synthesis were strongly reduced both in pine nut oil and maize oil-fed animals, thus suggesting that the beneficial effects of pine nut oil are not due to an inhibition of hepatic lipogenesis.
Clonal variations in nutritional components of Pinus koreansis seeds collected from seed orchards in Northeastern China
Zhen Zhang, Hanguo Zhang, Chuanping Yang, Lei Zhang, Jia Du, Ying Jiang
Journal of Forestry Research
Preparation of highly purified pinolenic acid from pine nut oil using a combination of enzymatic esterification and urea complexation
Da Som No, Ting Ting Zhao, Yangha Kim, Mi-Ra Yoon, Jeom-Sig Lee, In-Hwan Kim
Food Chemistry
Korean pine nut oil replacement decreases intestinal lipid uptake while improves hepatic lipid metabolism in mice
Shuang Zhu, Soyoung Park, Yeseo Lim, Sunhye Shin, Sung Nim Han
Nutrition Research and Practice
Impact of Korean pine nut oil on weight gain and immune responses in high-fat diet-induced obese mice
Soyoung Park, Yeseo Lim, Sunhye Shin, Sung Nim Han
Nutrition Research and Practice
Physiochemical and oxidative stability of interesterified structured lipid for soft margarine fat containing Δ5-UPIFAs
Xue-Mei Zhu, Jiang-Ning Hu, Cheng-Lian Xue, Jeung-Hee Lee, Jung-Ah Shin, Soon-Taek Hong, Chang-Keun Sung, Ki-Teak Lee
Food Chemistry
Chemical Composition of Pinus koraiensis Seed and Its Biological Activity
Ran Kim
KSBB Journal
Korean Pine Nut Oil Attenuated Hepatic Triacylglycerol Accumulation in High-Fat Diet-Induced Obese Mice
Soyoung Park, Sunhye Shin, Yeseo Lim, Jae Shin, Je Seong, Sung Han
Dietary Fat and Hepatic Lipogenesis: Mitochondrial Citrate Carrier as a Sensor of Metabolic Changes
Alessandra Ferramosca, Vincenzo Zara
Advances in Nutrition
Divergent Response of Murine and Porcine Adipocytes to Stimulation of Browning Genes by 18-Carbon Polyunsaturated Fatty Acids and Beta-Receptor Agonists
Sunhye Shin, Kolapo M. Ajuwon
Preparation of High Purity Δ5-Olefinic Acids from Pine Nut Oil via Repeated Lipase-Catalyzed Esterification
Heejin Kim, Nakyung Choi, Hak-Ryul Kim, Junsoo Lee, In-Hwan Kim
Journal of Oleo Science
Edible Medicinal And Non-Medicinal Plants
T. Lim
A Structured Pine Nut Oil Has Hypocholesterolemic Activity by Increasing LDLR Gene Expression in the Livers of Obese Mice
Min‐Yu Chung, Jiwon Kim, Hyo‐Kyoung Choi, Hee‐Don Choi, Sang Noh, Byung Kim
European Journal of Lipid Science and Technology
Cold Pressed Oils
Yasemin Incegul, Mehmet Aksu, Sündüz Kiralan, Mustafa Kiralan, Gulcan Ozkan
Estimation of Genetic Parameters and Wood Yield Selection Index in a Clonal Trial of Korean Pine (Pinus koraiensis) in Northeastern China
Kaviriri Kombi, Huan-Zhen Liu, Xi-Yang Zhao
A review of the functional effects of pine nut oil, pinolenic acid and its derivative eicosatrienoic acid and their potential health benefits
Ella Baker, Elizabeth Miles, Philip Calder
Progress in Lipid Research
Effect of an extract of Pinus koraiensis leaves, Lycium chinense fruit, and Saururus chinensis (Lour.) Baill. leaves on liver function in excessive drinkers: A randomized, double-blind, placebo-controlled trial
Ju Park, Min Bok, Jieun Kim, Sungho Maeng, Sung-Hoon Kim, Ji Jung, Hyo-Jung Lee, Hyunjung Lim
Journal of Functional Foods
Advances on delta 5-unsaturated-polymethylene-interrupted fatty acids: Resources, biosynthesis, and benefits
Lili Song, Sisi Wen, Qin Ye, Heqiang Lou, Yadi Gao, Vivek Bajpai, María Carpena, Miguel-Angel Prieto, Jesus Simal-Gandara, Jianbo Xiao, Xianghe Meng, Jiasheng Wu
Critical Reviews in Food Science and Nutrition
Stability and Bioaccessibility of Fucoxanthin in Nanoemulsions Prepared from Pinolenic Acid-contained Structured Lipid
Zhenghua Huang, Liqing Xu, Xuemei Zhu, Jiangning Hu, Hailong Peng, Zheling Zeng, Hua Xiong
International Journal of Food Engineering
Effects of Torreya grandis Kernel Oil on Lipid Metabolism and Intestinal Flora in C57BL/6J Mice
Minghui Xiao, Minjie Huang, Weiwei Huan, Jie Dong, Jianbo Xiao, Jiasheng Wu, Deqian Wang, Lili Song, Alessandra Durazzo
Oxidative Medicine and Cellular Longevity
Tolerability of graded levels of tall oil fatty acids as a nutritional additive for broiler chickens: a 45-day target animal safety study
H. Kettunen, M. Bento, E. Lewis, S. Remington, A. Matthews, S. Hendrix, Juhani Vuorenmaa
British Poultry Science
The Beneficial Effects of Pine Nuts and Its Major Fatty Acid, Pinolenic Acid, on Inflammation and Metabolic Perturbations in Inflammatory Disorders
Rabaa Takala, Dipak Ramji, Ernest Choy
International Journal of Molecular Sciences
Therapeutic Effects of Pinus koraiensis on 1-Fluoro-2,4-Dinitrofluorobenzene-induced Contact Dermatitis in Mice
Yuntae Kang, Seungyeop Oh, Yoorae Son, Wonjin Yang, Soyeon Kim, Ji-Hyo Lyu, Hyungwoo Kim
Pharmacognosy Magazine
Journals System - logo
Scroll to top