0.917
IF5
1.024
IF
Q2
JCR
0.90
CiteScore
0.385
SJR
Q2
SJR
20
MNiSW
142.18
ICV
ORIGINAL PAPER
 
CC-BY 4.0
 
 

Expression of IGFBP-3 and IGFBP-5 genes in muscles of pigs representing five different breeds

B. Rejduch 1,  
O. Oczkowicz 2  ,  
M. Witoń 2,  
M. Rogoz,  
 
1
National Research Institute of Animal Production, Department of Immuno and Cytogenetics, 32-083 Balice, Poland
2
National Research Institute of Animal Production, Department of Genetics and Animal Breeding, 32-083 Balice, Poland
J. Anim. Feed Sci. 2010;19(4):554–563
Publish date: 2010-11-26
KEYWORDS:
ABSTRACT:
Insuline like growth factors binding proteins (IGFBP 1-6) modulate action of insuline like growth factors (IGFs) - hormones engaged in the regulation of muscle growth of mammalian organism. The aim of our study was to analyse changes in the expression level of IGFBP-3 and IGFBP-5 genes in muscles during development of pigs (between 60 and 210 days of age) and to evaluate if there are differences in the expression level of these genes between groups of pigs representing different breeds. We did not observe a significant changes in IGFBP-5 mRNA level during postnatal development of pigs. However, IGFBP-3 was shown overexpressed at the early developmental stages, when compared to late developmental stages. The intra-breed analyses revealed that IGFBP-5 mRNA level was significantly lower in Duroc pigs and tract of IGFBP-3 was significantly higher in Pietrain pigs than in the other investigated breeds: Puławska, Polish Large White and Polish Landrace.
CORRESPONDING AUTHOR:
O. Oczkowicz   
National Research Institute of Animal Production, Department of Genetics and Animal Breeding, 32-083 Balice, Poland
 
CITATIONS (3):
1. Whole-genome association analysis of pork meat pH revealed three significant regions and several potential genes in Finnish Yorkshire pigs
Lucas L. Verardo, Marja-Liisa Sevón-Aimonen, Timo Serenius, Ville Hietakangas, Pekka Uimari
BMC Genetics
2. Quantitative Western ligand blotting reveals common patterns and differential features of IGFBP-fingerprints in domestic ruminant breeds and species
Elisa Wirthgen, Christine Höflich, Marion Spitschak, Carina Helmer, Bodo Brand, Jan Langbein, Friedrich Metzger, Andreas Hoeflich
Growth Hormone & IGF Research
3. Expression and imprinting analysis of the NESP55 gene in pigs
Maria Oczkowicz, Agata Piestrzyńska-Kajtoch, Katarzyna Ropka-Molik, Barbara Rejduch, Robert Eckert
Gene Expression Patterns
ISSN:1230-1388