ORIGINAL PAPER
Expression of Hoxa1 and Hoxd3 genes in chicken embryos with exencephaly
K. Jaszczak 1  
,   T. Malewski 1,   R. Parada 1,   H. Malec 2
 
More details
Hide details
1
Institute of Animal Genetics and Breeding, Polish Academy of Sciences, Jastrzębiec, 05-552 Wólka Kosowska, Poland
2
“MALEC” Hatchery, Dębówka 1a, 05-530 Góra Kalwaria, Poland
CORRESPONDING AUTHOR
K. Jaszczak   

Institute of Animal Genetics and Breeding, Polish Academy of Sciences, Jastrzębiec, 05-552 Wólka Kosowska, Poland
Publication date: 2006-07-05
 
J. Anim. Feed Sci. 2006;15(3):463–469
 
KEYWORDS
ABSTRACT
Analysis of skeletal malformations in embryos that died between day 17 and 21 of incubation obtained from two reproductive flocks of broiler chickens showed exencephaly to be the most common defect. It comprises about 48% of all diagnosed axial skeleton disorders. Analysis of the expression of Hoxa1 and Hoxd3 genes by real time PCR revealed upregulation of Hoxa1 in chicken embryos with exencephaly (16.8-fold higher), when compared with healthy birds. Upregulation of Hoxa1 suggests that this gene may be associated with exencephaly in chickens.
 
CITATIONS (6):
1.
Identification of Genes Related to Beak Deformity of Chickens Using Digital Gene Expression Profiling
Hao Bai, Jing Zhu, Yanyan Sun, Ranran Liu, Nian Liu, Dongli Li, Jie Wen, Jilan Chen, Marinus FW. te Pas
PLoS ONE
 
2.
Study on LOC426217 as a candidate gene for beak deformity in chicken
Hao Bai, Yanyan Sun, Jing Zhu, Nian Liu, Dongli Li, Fuguang Xue, Yunlei Li, Jilan Chen
BMC Genetics
 
3.
Pathology in Practice
Allison M. Watson, Tiffany L. Jenkins, Daniel R. Rissi
Journal of the American Veterinary Medical Association
 
4.
Single SNP- and pathway-based genome-wide association studies for beak deformity in chickens using high-density 600K SNP arrays
Hao Bai, Yanyan Sun, Nian Liu, Fuguang Xue, Yunlei Li, Songshan Xu, Jianhua Ye, Lei Zhang, Yu Chen, Jilan Chen
BMC Genomics
 
5.
Ectopic expression of Hoxb1 induces cardiac and craniofacial malformations
Stéphane Zaffran, Gaëlle Odelin, Sonia Stefanovic, Fabienne Lescroart, Heather C. Etchevers
genesis
 
6.
Comparison of inherited neural tube defects in companion animals and livestock
Alexandra Zarzycki, Zoe Thomas, Hamutal Mazrier
Birth Defects Research
 
ISSN:1230-1388