ORIGINAL PAPER
Expression of Hoxa1 and Hoxd3 genes in chicken
embryos with exencephaly
| 1 | Institute of Animal Genetics and Breeding, Polish Academy of Sciences,
Jastrzębiec, 05-552 Wólka Kosowska, Poland |
| 2 | “MALEC” Hatchery,
Dębówka 1a, 05-530 Góra Kalwaria, Poland |
CORRESPONDING AUTHOR
K. Jaszczak
Institute of Animal Genetics and Breeding, Polish Academy of Sciences, Jastrzębiec, 05-552 Wólka Kosowska, Poland
Institute of Animal Genetics and Breeding, Polish Academy of Sciences, Jastrzębiec, 05-552 Wólka Kosowska, Poland
Publication date: 2006-07-05
J. Anim. Feed Sci. 2006;15(3):463–469
KEYWORDS
ABSTRACT
Analysis of skeletal malformations in embryos that died between day 17 and 21 of incubation
obtained from two reproductive flocks of broiler chickens showed exencephaly to be the most
common defect. It comprises about 48% of all diagnosed axial skeleton disorders. Analysis of the
expression of Hoxa1 and Hoxd3 genes by real time PCR revealed upregulation of Hoxa1 in chicken
embryos with exencephaly (16.8-fold higher), when compared with healthy birds. Upregulation of
Hoxa1 suggests that this gene may be associated with exencephaly in chickens.
CITATIONS (6):
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