Exogenous leptin does not affect exocrine
pancreatic secretion in conscious sheep

W. Korczyński; D. Kirat; S. Kato

doi:10.22358/jafs/74379/2004

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About the Journal Editorial Office Editorial Board Copy right and self-archiving policy Peer review process Instructions for Reviewers Printed version subscription Abstracting and indexing Contact

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Suppl. 1/2004 vol. 13

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SHORT COMMUNICATION

Exogenous leptin does not affect exocrine pancreatic secretion in conscious sheep

W. Korczyński ¹

D. Kirat ²

S. Kato ²

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The Kielanowski Institute of Animal Physiology and Nutrition, Polish Academy of Sciences, 05-110 Jabłonna, Poland

Department of Physiology, School of Veterinary Medicine, Rakuno Gakuen University, Ebetsu, 069-8501 Hokkaido, Japan

Publication date: 2004-08-30

Corresponding author

W. Korczyński

The Kielanowski Institute of Animal Physiology and Nutrition, Polish Academy of Sciences, 05-110 Jabłonna, Poland

J. Anim. Feed Sci. 2004;13(Suppl. 1):425-428

DOI: https://doi.org/10.22358/jafs/74379/2004

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KEYWORDS

leptin

exocrine pancreatic secretion

electromyography

sheep

ABSTRACT

The experiment was performed on 10 Black Suffolk sheep of 59±8 kg BW. The animals were equipped with two catheters in common bile duct and one in duodenum and set of three bipolar electrodes sutured on the duodenum. In accordance to duodenal electromyography activity, effect of exogenous leptin on pancreatic juice secretion was studied. Administration of leptin (2-10 μg kg-¹ BW intravenously) did not affect the volume, protein, amylase and bicarbonates output in pancreatic juice. In conclusion, the results suggest, that in the doses used, leptin have no effect on pancreatic secretion.

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