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ORIGINAL PAPER
 
CC-BY 4.0
 
 

A note on biallelic expression of the IGF2 gene in the liver and brain of adult pigs

M. Wrzeska 1  ,  
A. Żyga 1,  
B. Rejduch 1,  
 
1
National Research Institute of Animal Production, Department of Immuno- and Cytogenetics of Animals, Krakowska 1, 32-083 Balice, Poland
J. Anim. Feed Sci. 2006;15(1):57–60
Publish date: 2006-01-06
KEYWORDS
ABSTRACT
The IGF2 gene is imprinted in most mammalian tissues. Considering the potential large impact of the IGF2 gene on breeding industry, further studies on IGF2 expression in various tissues and at different stages of animal’s development are required. Samples of blood, muscle, kidney, liver and brain were taken from 5.5-month-old pigs. Animals heterozygous for SWC9 marker were selected. RNA was isolated from the muscle, kidney, liver and brain and RT-PCR was performed. The results of the study showed that there is a relaxation of imprinting of the IGF2 gene in the liver and brain of adult pigs.
CORRESPONDING AUTHOR
M. Wrzeska   
National Research Institute of Animal Production, Department of Immuno- and Cytogenetics of Animals, Krakowska 1, 32-083 Balice, Poland
 
CITATIONS (5):
1. Dietary betaine supplementation to gestational sows enhances hippocampal IGF2 expression in newborn piglets with modified DNA methylation of the differentially methylated regions
Xi Li, Qinwei Sun, Xian Li, Demin Cai, Shiyan Sui, Yimin Jia, Haogang Song, Ruqian Zhao
European Journal of Nutrition
2. Variation in the IGF2 gene promoter region is associated with intramuscular fat content in porcine skeletal muscle
Ozlem Aslan, Ruth M. Hamill, Grace Davey, Jean McBryan, Anne Maria Mullen, Marina Gispert, Torres Sweeney
Molecular Biology Reports
3. Lack of the Associations of the Polymorphisms inIGF2, MC4RandGNASGenes with Reproduction Traits in Pigs and Imprinting Analysis ofIGF2Gene in Ovary andCornus Uteri
M Oczkowicz, A Mucha, M Tyra, K Ropka-Molik, K Piórkowska
Reproduction in Domestic Animals
4. Effect of IGF2 intron3-g.3072G>A on intramuscular fat (IMF) content in pigs raised in Poland
Maria Oczkowicz, Mirosław Tyra, Katarzyna Ropka-Molik, Aurelia Mucha, Kacper Żukowski
Livestock Science
5. The insulin-like growth factor 2 (IGF2) gene intron3-g.3072G>A polymorphism is not the only Sus scrofa chromosome 2p mutation affecting meat production and carcass traits in pigs: Evidence from the effects of a cathepsin D (CTSD) gene polymorphism1
L. Fontanesi, C. Speroni, L. Buttazzoni, E. Scotti, S. Dall'Olio, L. Nanni Costa, R. Davoli, V. Russo
Journal of Animal Science
ISSN:1230-1388