Preliminary results on exogenous ghrelin
administration  via  stomach tube influence on the crypt
cell proliferation in the small intestine mucosa
of neonatal piglets

M. Słupecka; J. Woliński

doi:10.22358/jafs/66800/2007

Current issue Online first Archive About the Journal Editorial Office Editorial Board Copy right and self-archiving policy Peer review process Instructions for Reviewers Printed version subscription Abstracting and indexing Contact Instructions for Authors Policies General information Open Access, Licensing terms, Commercial use and Copyright terms policies Self-archiving policy and Archive policies Article Correction and Withdrawal policy Manuscript Submission policy Authorship policy Conflict of Interest policy Language considerations policy Plagiarism and Duplicate publications policy Ethics policy Review process policy Acceptance of manuscripts policy Online First Articles and Special Issues policies Generative artificial intelligence (AI) policy Advertising policy Article publication charges

Current issue

Online first

Archive

About the Journal Editorial Office Editorial Board Copy right and self-archiving policy Peer review process Instructions for Reviewers Printed version subscription Abstracting and indexing Contact

Instructions for Authors

Policies General information Open Access, Licensing terms, Commercial use and Copyright terms policies Self-archiving policy and Archive policies Article Correction and Withdrawal policy Manuscript Submission policy Authorship policy Conflict of Interest policy Language considerations policy Plagiarism and Duplicate publications policy Ethics policy Review process policy Acceptance of manuscripts policy Online First Articles and Special Issues policies Generative artificial intelligence (AI) policy Advertising policy

Article publication charges

3/2007 vol. 16

Stats

CC-BY 4.0

Get citation

ORIGINAL PAPER

Preliminary results on exogenous ghrelin administration via stomach tube influence on the crypt cell proliferation in the small intestine mucosa of neonatal piglets

M. Słupecka ¹

J. Woliński ¹

More details

Hide details

The Kielanowski Institute of Animal Physiology and Nutrition, Department of Gastrointestinal Physiology, Polish Academy of Sciences, 05-110 Jabłonna, Poland

Publication date: 2007-09-06

Corresponding author

M. Słupecka

The Kielanowski Institute of Animal Physiology and Nutrition, Department of Gastrointestinal Physiology, Polish Academy of Sciences, 05-110 Jabłonna, Poland

J. Anim. Feed Sci. 2007;16(3):445-451

DOI: https://doi.org/10.22358/jafs/66800/2007

Article (PDF)

Citations (3)

KEYWORDS

ghrelin

proliferation

small intestine

piglets

ABSTRACT

The aim of this study was to investigate the exogenous ghrelin effect on proliferation in the small intestinal mucosa, body and organs weight of neonatal piglets. Four groups (n=6) of pig neonates were examined: sow reared (C7SR), fed with milk formula (C7), fed with milk formula + ghrelin administrated via stomach tube in the dose of: 7.5 μg/kg body weight (BW) (G7.5) and 15 μg/kg BW (G15). Milk formula feeding (C7) strongly decreased mitotic rate in all parts of jejunum as compared to C7SR. Ghrelin treatment (G7.5) had a pro mitotic effect on the middle part of the small intestine (P<0.0001) as compared to C7. G15 treatment strongly increased the mitotic activity as compared to C7 (P<0.0001) and C7SR (P<0.0001). Unlike other forms of treatment in G15 mitotic activity was constant along all parts of small intestine. Moreover, ghrelin treatment decreased BW and increased stomach weight. In conclusion, exogenous ghrelin administrated in the dose of 15 μg/kg BW for 6 days resulted in the increase of the crypt cell proliferation in the small intestine mucosa of neonatal piglets.

CITATIONS (3):

Crypt fission contributes to postnatal epithelial growth of the small intestine in pigs
M. Słupecka, J. Woliński, S.G. Pierzynowski
Livestock Science

CrossRef

Effect of in ovo ghrelin administration on hatching results and post-hatching performance of broiler chickens
A. Lotfi, H. Aghdam Shahryar, H. Kaiya
Livestock Science

CrossRef

Ghrelin modulates innate immune and ileal responses to lipopolysaccharide administration in weaned pigs
Nicole C. Burdick Sanchez, Jeffery W. Dailey, Paul R. Broadway, Emily M. Davis, Brooke M. Bowen, Amy L. Petry, Michael A. Ballou, Kristin E. Hales, Jeffery A. Carroll
Frontiers in Animal Science

CrossRef

Submit your paper

Instructions for Authors

Archive

Send by email

Effectiveness of emulsifier and carbohydrase in Lupinus albus seed-rich diets on digestibility, some physiological indicators and performance of growing pigs

Sodium selenite addition promotes the proliferation of bovine mammary epithelial cells through the Akt-mTOR signalling pathway

Effects of different selenium sources on sow reproductive performance and piglet development: a meta-analysis

Effects of maternal vitamin D₃ status on meat quality and fatty acids composition in offspring pigs

Effect of pidotimod on growth performance, immune function, intestinal epithelial barriers and microbiota of piglets

Indexes

Keywords index

Topics index

Authors index

ISSN:

1230-1388

Assigning DOI numbers, introducing articles from supplements and recent publications to POL-index database, maintaining anti-plagiarism detection, electronic system to proceed manuscripts and webpage of the Journal with interactive pdf files, and language correction of manuscripts published in Journal of Animal and Feed Sciences are financed in the years 2018–2019 by the Ministry of Science and Higher Education from the funds for science popularization activities, Agreement No. 631/P-DUN/2018.