0.857
IF5
0.900
IF
Q3
JCR
0.92
CiteScore
0.405
SJR
Q2
SJR
20
MNiSW
165.24
ICV
ORIGINAL PAPER
 
CC-BY 4.0
 
 

The effect of dietary conjugated linoleic acid on the levels of lipids, cholesterol and iodothyronines in the blood of pigs

A. Sechman 1  ,  
M. Pieszka 2,  
J. Rząsa 1,  
W. Migdał 3,  
D. Wojtysiak 4,  
H. Pustkowiak 5,  
B. Živković 6,  
 
1
Agricultural University in Krakow, Department of Animal Physiology, al. Mickiewicza 24/28, 30-059 Kraków, Poland
2
National Research Institute of Animal Production, 32-083 Balice, Poland
3
Agricultural University in Krakow, Department of Animal Products Technology, Balicka 122, 31-149 Kraków, Poland
4
Agricultural University in Krakow, Department of Reproduction and Animal Anatomy, al. Mickiewicza 24/28, 30-059 Kraków, Poland
5
Agricultural University in Krakow, Department of Cattle Breeding, al. Mickiewicza 24/28, 30-059 Kraków, Poland
6
Institute for Animal Husbandry, 11080 Zemun, Autoput 16, Serbia and Montenegro
7
Ecopig Ltd., 42-510 Wojkowice Kościelne, Poland
J. Anim. Feed Sci. 2007;16(2):193–204
Publish date: 2007-05-02
KEYWORDS
ABSTRACT
The aim of the investigation was to study the effect of dietary conjugated linoleic acid (CLA) on the concentrations of lipids, fatty acids and iodothyronines: thyroxine (T4), triiodothyronine (T3), reverse-triiodothyronine (rT3), free T4 (FT4) and free T3 (FT3) in blood plasma of pigs. The experiment was carried out on 50 fatteners (average liveweight 50 kg) divided into 5 groups (5 gilts and 5 barrows per group). The pigs were fed a basal diet supplemented with 0, 0.5, 1, 1.5 and 2% of CLA isomers. Blood samples were collected from fatteners weighing 105 kg. Supplementation of the diet with CLA did not significantly affect lipid parameters in blood plasma. In comparison with gilts, a significantly higher concentration of triglycerides in barrows was found. In CLA-fed pigs, significant changes in the plasma fatty acid profile were noticed. The higher doses of CLA caused a significant increase in CLA and saturated fatty acids (SFA) with a concomitant decrease in monounsaturated (MUFA) and polyunsaturated (PUFA) fatty acids in blood plasma. Moreover, dietary CLA decreased the ∆9 desaturase index in a dose-dependent manner, probably as a result of the inhibitory effect of CLA on stearoyl-CoA activity.Only the lowest dose of CLA (0.5%) increased T 4 and T3 concentrations in blood plasma of fatteners by 64 and 27%, respectively. There were no significant changes in rT3, FT4 and FT3 in the plasma of CLA-treated pigs. The results obtained indicate that dietary CLA influenced the fatty acid profile in blood plasma of fatteners without affecting basic lipid parameters. The increase in T4 and T3 concentrations in the blood of CLAtreated pigs suggests that low doses of CLA may stimulate the function of the pituitary-thyroid axis and/or deiodinase activity. On the other hand, the absence of changes in FT4 and FT3 indicates that CLA treatment does not affect thyroid hormone homeostasis in blood.
CORRESPONDING AUTHOR
A. Sechman   
Agricultural University in Krakow, Department of Animal Physiology, al. Mickiewicza 24/28, 30-059 Kraków, Poland
 
CITATIONS (1):
1. Dietary conjugated linoleic acid (CLA) has comparable effects to ractopamine on the growth performance, meat quality and fatty acid profiles of loin muscles of finishing pigs under commercial husbandry
Araceli Pinelli-Saavedra, Humberto González-Ríos, José Luis Dávila-Ramírez, Thalia Yamileth Islava-Lagarda, Ingrid Rebeca Esquerra-Brauer
Italian Journal of Animal Science
ISSN:1230-1388