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Insect proteins as a potential source of antimicrobial peptides in livestock production. A review

A. Józefiak 1  ,  
R. M. Engberg 2
 
1
Poznań University of Life Sciences, Institute of Veterinary Sciences, Wołyńska 35, 60-637 Poznań, Poland
2
Aarhus University, Department of Animal Science, Blichers Allé 20, 8830 Tjele, Denmark
J. Anim. Feed Sci. 2017;26(2):87–99
Publication date: 2017-05-15
DOI: https://doi.org/10.22358/jafs/69998/2017
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References (86) Citations (33)
 
KEYWORDS
insect AMPs, antimicrobial activity, defensins, bacterial resistance, dietary supplementation, livestock production
TOPICS
feed additives, insects, microbiology, molecular biology, nutrition
ABSTRACT
Together with the extraction of first insect antimicrobial protein (AMP) from the pupae of the giant silk moths Hyalophora cecropia the antibacterial activity of insects was observed for the first time in 1980. Practically, AMPs are small, cationic proteins that exhibit activity against bacteria, fungi as well as certain parasites and viruses. It is known that in addition to their antimicrobial effect, they boost host specific innate immune responses and exert selective immunomodulatory effects involved in angiogenesis and wound healing. More than 1,500 proteins with antimicrobial activity have been identified in different organisms, including plants, fungi, bacteria and animals. Insects are a primary source of AMPs which are considered as not resulting in the development of natural bacterial resistance. In general, they are characterized as heat-stable with no adverse effects on eukaryotic cells. These characteristics contribute to the potential use of these proteins in human and veterinary medicine and in animal nutrition. Depending on their mode of action, insect AMPs may be applied as single peptides, as a complex of different AMPs and as an active fraction of insect proteins in the nutrition of different livestock. The great potential for the use of AMPs in animal production is primarily associated with the growing problem of antibiotics resistance, which has triggered the search for alternatives to antibiotics in livestock production. The review presents the current knowledge of insect AMPs, their chemical structure and mode of action with focus on their potential use in agriculture and livestock production.
CORRESPONDING AUTHOR
A. Józefiak   
Poznań University of Life Sciences, Institute of Veterinary Sciences, Wołyńska 35, 60-637 Poznań, Poland
 
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12. Combined effect of the entomopathogenic fungus Metarhizium robertsii and avermectins on the survival and immune response of Aedes aegypti larvae
Yuriy Noskov, Olga Polenogova, Olga Yaroslavtseva, Olga Belevich, Yuriy Yurchenko, Ekaterina Chertkova, Natalya Kryukova, Vadim Kryukov, Viktor Glupov
PeerJ
13. Antibacterial activity of a Tribolium castaneum defensin in an in vitro infection model of Streptococcus pneumoniae
Nora Lindhauer, Wilhelm Bertrams, Anne Pöppel, Christina Herkt, Andre Wesener, Kerstin Hoffmann, Brandon Greene, Der Van, Andreas Vilcinskas, Kerstin Seidel, Bernd Schmeck
Virulence
14. Insect larvae, Hermetia illucens in poultry by-product meal for barramundi, Lates calcarifer modulates histomorphology, immunity and resistance to Vibrio harveyi
Md Chaklader, Muhammad Siddik, Ravi Fotedar, Janet Howieson
Scientific Reports
15. Insect Cecropins, Antimicrobial Peptides with Potential Therapeutic Applications
Daniel Brady, Alessandro Grapputo, Ottavia Romoli, Federica Sandrelli
International Journal of Molecular Sciences
16. Replacement of soybean oil by Hermetia illucens fat in turkey nutrition: effect on performance, digestibility, microbial community, immune and physiological status and final product quality
J. Sypniewski, B. Kierończyk, A. Benzertiha, Z. Mikołajczak, E. Pruszyńska-Oszmałek, P. Kołodziejski, M. Sassek, M. Rawski, W. Czekała, D. Józefiak
British Poultry Science
17. Listeria dynamics in a laboratory-scale food chain of mealworm larvae (Tenebrio molitor) intended for human consumption
Luca Belleggia, Vesna Milanović, Federica Cardinali, Cristiana Garofalo, Marina Pasquini, Stefano Tavoletti, Paola Riolo, Sara Ruschioni, Nunzio Isidoro, Francesca Clementi, Athanasios Ntoumos, Lucia Aquilanti, Andrea Osimani
Food Control
18. Improvement of Cecal Commensal Microbiome Following the Insect Additive into Chicken Diet
Agata Józefiak, Abdelbasset Benzertiha, Bartosz Kierończyk, Anna Łukomska, Izabela Wesołowska, Mateusz Rawski
Animals
19. Insect and fish by-products as sustainable alternatives to conventional animal proteins in animal nutrition
Laura Gasco, Gabriele Acuti, Paolo Bani, Zotte Dalle, Pier Danieli, Angelis De, Riccardo Fortina, Rosaria Marino, Giuliana Parisi, Giovanni Piccolo, Luciano Pinotti, Aldo Prandini, Achille Schiavone, Genciana Terova, Francesca Tulli, Alessandra Roncarati
Italian Journal of Animal Science
20. ПОЛУЧЕНИЕ ВОДОРАСТВОРИМЫХ ПЕПТИДОВ ИЗ БИОМАССЫ ЛИЧИНОК MUSCA DOMESTICA И ИЗУЧЕНИЕ ИХ СВОЙСТВ
Крылова Л.С., Ремизов Е.К., Смирнова К.Ю., Сорокатая Е.И., Древко Я.Б.
Bulletin of KSAU
21. An Enhanced Variant Designed From DLP4 Cationic Peptide Against Staphylococcus aureus CVCC 546
Bing Li, Na Yang, Xiumin Wang, Ya Hao, Ruoyu Mao, Zhanzhan Li, Zhenlong Wang, Da Teng, Jianhua Wang
Frontiers in Microbiology
22. Potential of Black Soldier Fly Production for Pacific Small Island Developing States
Matan Shelomi
Animals
23. Antioxidant Status and Liver Function of Young Turkeys Receiving a Diet with Full-Fat Insect Meal from Hermetia illucens
Katarzyna Ognik, Krzysztof Kozłowski, Anna Stępniowska, Piotr Listos, Damian Józefiak, Zenon Zduńczyk, Jan Jankowski
Animals
24. Locusta migratoria extruded meal in young steers diet: evaluation of growth performance, blood indices and meat traits of Calves Kasakh white-headed breed
Ivan Gorlov, Marina Slozhenkina, Natalia Mosolova, Vladimir Grishin, Aleksandr Mosolov, Elena Bondarkova, Elena Anisimova, Yulia Starodubova, Svetlana Brekhova, Pavel Andreev-Chadaev
Journal of Applied Animal Research
25. Bacterial but not fungal challenge up-regulates the transcription of Coleoptericin genes in Tenebrio molitor
Ho Jang, Ki Park, Bo Kim, Mohammadie Ali, Young Bae, Snigdha Baliarsingh, Yong Lee, Yeon Han, Yong Jo
Entomological Research
26. Biosurfactants Induce Antimicrobial Peptide Production through the Activation of TmSpatzles in Tenebrio molitor
Tariku Edosa, Yong Jo, Maryam Keshavarz, In Kim, Yeon Han
International Journal of Molecular Sciences
27. Growth Performance and Adaptability of European Sea Bass (Dicentrarchus labrax) Gut Microbiota to Alternative Diets Free of Fish Products
David Pérez-Pascual, Jordi Estellé, Gilbert Dutto, Charles Rodde, Jean-François Bernardet, Yann Marchand, Eric Duchaud, Cyrille Przybyla, Jean-Marc Ghigo
Microorganisms
28. Antioxidant enzyme regulating and intracellular ROS scavenging capacities of two novel bioactive peptides from white grub larvae (Polyphylla adstpersa) hydrolysate in A549 cells
Asal Khajepour-Zaveh, Ahmad Asoodeh, Hossein Naderi-Manesh
Medicinal Chemistry Research
29. A bioinformatic study of antimicrobial peptides identified in the Black Soldier Fly (BSF) Hermetia illucens (Diptera: Stratiomyidae)
Antonio Moretta, Rosanna Salvia, Carmen Scieuzo, Somma Di, Heiko Vogel, Pietro Pucci, Alessandro Sgambato, Michael Wolff, Patrizia Falabella
Scientific Reports
30. Enhanced Antioxidant and Cytotoxic Potentials of Lipopolysaccharides-Injected Musca domestica Larvae
Islam El-Garawani, Hesham El-Seedi, Shaden Khalifa, Azab El, Marwa Abouhendia, Shaymaa Mahmoud
Pharmaceutics
31. Gut immunity in European sea bass (Dicentrarchus labrax): a review
S. Picchietti, A. Miccoli, A.M. Fausto
Fish & Shellfish Immunology
32. Last Call for Replacement of Antimicrobials in Animal Production: Modern Challenges, Opportunities, and Potential Solutions
Aneta Nowakiewicz, Przemysław Zięba, Sebastian Gnat, Łukasz Matuszewski
Antibiotics
33. Alternative Protein Sources vs. GM Soybean Meal as Feedstuff for Pigs—Meat Quality and Health-Promoting Indicators
Marcin Sońta, Anna Rekiel, Justyna Więcek, Martyna Batorska, Kamila Puppel
Animals
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ISSN:1230-1388
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