Insect proteins as a potential source of antimicrobial peptides in livestock production. A review
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Poznań University of Life Sciences, Institute of Veterinary Sciences, Wołyńska 35, 60-637 Poznań, Poland
Aarhus University, Department of Animal Science, Blichers Allé 20, 8830 Tjele, Denmark
A. Józefiak   

Poznań University of Life Sciences, Institute of Veterinary Sciences, Wołyńska 35, 60-637 Poznań, Poland
Publication date: 2017-05-15
J. Anim. Feed Sci. 2017;26(2):87–99
Together with the extraction of first insect antimicrobial protein (AMP) from the pupae of the giant silk moths Hyalophora cecropia the antibacterial activity of insects was observed for the first time in 1980. Practically, AMPs are small, cationic proteins that exhibit activity against bacteria, fungi as well as certain parasites and viruses. It is known that in addition to their antimicrobial effect, they boost host specific innate immune responses and exert selective immunomodulatory effects involved in angiogenesis and wound healing. More than 1,500 proteins with antimicrobial activity have been identified in different organisms, including plants, fungi, bacteria and animals. Insects are a primary source of AMPs which are considered as not resulting in the development of natural bacterial resistance. In general, they are characterized as heat-stable with no adverse effects on eukaryotic cells. These characteristics contribute to the potential use of these proteins in human and veterinary medicine and in animal nutrition. Depending on their mode of action, insect AMPs may be applied as single peptides, as a complex of different AMPs and as an active fraction of insect proteins in the nutrition of different livestock. The great potential for the use of AMPs in animal production is primarily associated with the growing problem of antibiotics resistance, which has triggered the search for alternatives to antibiotics in livestock production. The review presents the current knowledge of insect AMPs, their chemical structure and mode of action with focus on their potential use in agriculture and livestock production.
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Gut immunity in European sea bass (Dicentrarchus labrax): a review
S. Picchietti, A. Miccoli, A.M. Fausto
Fish & Shellfish Immunology
Last Call for Replacement of Antimicrobials in Animal Production: Modern Challenges, Opportunities, and Potential Solutions
Aneta Nowakiewicz, Przemysław Zięba, Sebastian Gnat, Łukasz Matuszewski
Alternative Protein Sources vs. GM Soybean Meal as Feedstuff for Pigs—Meat Quality and Health-Promoting Indicators
Marcin Sońta, Anna Rekiel, Justyna Więcek, Martyna Batorska, Kamila Puppel
Use of black soldier fly and house fly in feed to promote sustainable poultry production
A. Dörper, T. Veldkamp, M. Dicke
Journal of Insects as Food and Feed
Beyond the protein concept: health aspects of using edible insects on animals
L. Gasco, A. Józefiak, M. Henry
Journal of Insects as Food and Feed
The effect of dietary full-fat Hermetia illucens larvae meal on gut physiology and growth performance in young turkeys
Jan Jankowski, Krzysztof Kozłowski, Zenon Zduńczyk, Anna Stępniowska, Katarzyna Ognik, Bartosz Kierończyk, Damian Józefiak, Jerzy Juśkiewicz
Animal Feed Science and Technology
Total replacement of fish meal by enriched‐fatty acid Hermetia illucens meal did not substantially affect growth parameters or innate immune status and improved whole body biochemical quality of Nile tilapia juveniles
Pamphile Agbohessou, Syaghalirwa Mandiki, Armel Gougbédji, Rudy Megido, Md. Hossain, Jaeger De, Yvan Larondelle, Frédéric Francis, Philippe Lalèyè, Patrick Kestemont
Aquaculture Nutrition
Feasibility of superworm, Zophobas morio , meal as a partial fishmeal replacer in fingerling rainbow trout, Oncorhynchus mykiss , diet: growth performance, amino acid profile, proteolytic enzymes activity and pigmentation
Shekarabi Hosseini, Mehrgan Shamsaie, Akbar Banavreh
Aquaculture Nutrition
Identification of a novel proline‐rich antimicrobial protein from the hemolymph of Antheraea mylitta
Trinath Chowdhury, Santi Mandal, Soumita Dutta, Ananta Ghosh
Archives of Insect Biochemistry and Physiology
Antibacterial activity of selected invertebrate species
Salwa Ali, Ruqaiyayh Siddiqui, Kuppusamy Sagathevan, Naveed Khan
Folia Microbiologica
Performance, nutrient digestibility and selected gut health parameters of broilers fed with black soldier fly, lesser mealworm and yellow mealworm
der Van, J.V. Nørgaard, R.M. Engberg
Journal of Insects as Food and Feed