REVIEW PAPER
Insect proteins as a potential source of antimicrobial peptides
in livestock production. A review
| 1 | Poznań University of Life Sciences, Institute of Veterinary Sciences, Wołyńska 35, 60-637 Poznań, Poland |
| 2 | Aarhus University, Department of Animal Science, Blichers Allé 20, 8830 Tjele, Denmark |
CORRESPONDING AUTHOR
A. Józefiak
Poznań University of Life Sciences, Institute of Veterinary Sciences, Wołyńska 35, 60-637 Poznań, Poland
Poznań University of Life Sciences, Institute of Veterinary Sciences, Wołyńska 35, 60-637 Poznań, Poland
Publication date: 2017-05-15
J. Anim. Feed Sci. 2017;26(2):87–99
KEYWORDS
insect AMPsantimicrobial activitydefensinsbacterial resistancedietary supplementationlivestock production
TOPICS
ABSTRACT
Together with the extraction of first insect antimicrobial protein
(AMP) from the pupae of the giant silk moths Hyalophora cecropia the antibacterial
activity of insects was observed for the first time in 1980. Practically, AMPs
are small, cationic proteins that exhibit activity against bacteria, fungi as well as
certain parasites and viruses. It is known that in addition to their antimicrobial
effect, they boost host specific innate immune responses and exert selective
immunomodulatory effects involved in angiogenesis and wound healing. More
than 1,500 proteins with antimicrobial activity have been identified in different
organisms, including plants, fungi, bacteria and animals. Insects are a primary
source of AMPs which are considered as not resulting in the development of
natural bacterial resistance. In general, they are characterized as heat-stable
with no adverse effects on eukaryotic cells. These characteristics contribute to
the potential use of these proteins in human and veterinary medicine and in animal
nutrition. Depending on their mode of action, insect AMPs may be applied
as single peptides, as a complex of different AMPs and as an active fraction
of insect proteins in the nutrition of different livestock. The great potential for
the use of AMPs in animal production is primarily associated with the growing
problem of antibiotics resistance, which has triggered the search for alternatives
to antibiotics in livestock production. The review presents the current knowledge
of insect AMPs, their chemical structure and mode of action with focus on their
potential use in agriculture and livestock production.
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Ecology and Evolution
7.
A case report on inVALUABLE: insect value chain in a circular bioeconomy
L.-H. Heckmann, J.L. Andersen, J. Eilenberg, J. Fynbo, R. Miklos, A.N. Jensen, J.V. Nørgaard, N. Roos
Journal of Insects as Food and Feed
L.-H. Heckmann, J.L. Andersen, J. Eilenberg, J. Fynbo, R. Miklos, A.N. Jensen, J.V. Nørgaard, N. Roos
Journal of Insects as Food and Feed
8.
Consumer acceptance of insects as food and feed: the relevance of affective factors
M.C. Onwezen, den van, M.C.D. Verain, T. Veldkamp
Food Quality and Preference
M.C. Onwezen, den van, M.C.D. Verain, T. Veldkamp
Food Quality and Preference
9.
Review: Insect meal: a future source of protein feed for pigs?
K. DiGiacomo, B. Leury
animal
K. DiGiacomo, B. Leury
animal
10.
Tenebrio molitor and Zophobas morio full-fat meals as functional feed additives affect broiler chickens’ growth performance and immune system traits
A Benzertiha, B Kierończyk, P Kołodziejski, E Pruszyńska–Oszmałek, M Rawski, D Józefiak, A Józefiak
Poultry Science
A Benzertiha, B Kierończyk, P Kołodziejski, E Pruszyńska–Oszmałek, M Rawski, D Józefiak, A Józefiak
Poultry Science
11.
Effects of insect diets on the gastrointestinal tract health and growth performance of Siberian sturgeon (Acipenser baerii Brandt, 1869)
Agata Józefiak, Silvia Nogales-Mérida, Mateusz Rawski, Bartosz Kierończyk, Jan Mazurkiewicz
BMC Veterinary Research
Agata Józefiak, Silvia Nogales-Mérida, Mateusz Rawski, Bartosz Kierończyk, Jan Mazurkiewicz
BMC Veterinary Research
12.
Combined effect of the entomopathogenic fungus Metarhizium robertsii and avermectins on the survival and immune response of Aedes aegypti larvae
Yuriy Noskov, Olga Polenogova, Olga Yaroslavtseva, Olga Belevich, Yuriy Yurchenko, Ekaterina Chertkova, Natalya Kryukova, Vadim Kryukov, Viktor Glupov
PeerJ
Yuriy Noskov, Olga Polenogova, Olga Yaroslavtseva, Olga Belevich, Yuriy Yurchenko, Ekaterina Chertkova, Natalya Kryukova, Vadim Kryukov, Viktor Glupov
PeerJ
13.
Antibacterial activity of a Tribolium castaneum defensin in an in vitro infection model of Streptococcus pneumoniae
Nora Lindhauer, Wilhelm Bertrams, Anne Pöppel, Christina Herkt, Andre Wesener, Kerstin Hoffmann, Brandon Greene, Der Van, Andreas Vilcinskas, Kerstin Seidel, Bernd Schmeck
Virulence
Nora Lindhauer, Wilhelm Bertrams, Anne Pöppel, Christina Herkt, Andre Wesener, Kerstin Hoffmann, Brandon Greene, Der Van, Andreas Vilcinskas, Kerstin Seidel, Bernd Schmeck
Virulence
14.
Insect larvae, Hermetia illucens in poultry by-product meal for barramundi, Lates calcarifer modulates histomorphology, immunity and resistance to Vibrio harveyi
Md Chaklader, Muhammad Siddik, Ravi Fotedar, Janet Howieson
Scientific Reports
Md Chaklader, Muhammad Siddik, Ravi Fotedar, Janet Howieson
Scientific Reports
15.
Insect Cecropins, Antimicrobial Peptides with Potential Therapeutic Applications
Daniel Brady, Alessandro Grapputo, Ottavia Romoli, Federica Sandrelli
International Journal of Molecular Sciences
Daniel Brady, Alessandro Grapputo, Ottavia Romoli, Federica Sandrelli
International Journal of Molecular Sciences
16.
Replacement of soybean oil by Hermetia illucens fat in turkey nutrition: effect on performance, digestibility, microbial community, immune and physiological status and final product quality
J. Sypniewski, B. Kierończyk, A. Benzertiha, Z. Mikołajczak, E. Pruszyńska-Oszmałek, P. Kołodziejski, M. Sassek, M. Rawski, W. Czekała, D. Józefiak
British Poultry Science
J. Sypniewski, B. Kierończyk, A. Benzertiha, Z. Mikołajczak, E. Pruszyńska-Oszmałek, P. Kołodziejski, M. Sassek, M. Rawski, W. Czekała, D. Józefiak
British Poultry Science
17.
Listeria dynamics in a laboratory-scale food chain of mealworm larvae (Tenebrio molitor) intended for human consumption
Luca Belleggia, Vesna Milanović, Federica Cardinali, Cristiana Garofalo, Marina Pasquini, Stefano Tavoletti, Paola Riolo, Sara Ruschioni, Nunzio Isidoro, Francesca Clementi, Athanasios Ntoumos, Lucia Aquilanti, Andrea Osimani
Food Control
Luca Belleggia, Vesna Milanović, Federica Cardinali, Cristiana Garofalo, Marina Pasquini, Stefano Tavoletti, Paola Riolo, Sara Ruschioni, Nunzio Isidoro, Francesca Clementi, Athanasios Ntoumos, Lucia Aquilanti, Andrea Osimani
Food Control
18.
Improvement of Cecal Commensal Microbiome Following the Insect Additive into Chicken Diet
Agata Józefiak, Abdelbasset Benzertiha, Bartosz Kierończyk, Anna Łukomska, Izabela Wesołowska, Mateusz Rawski
Animals
Agata Józefiak, Abdelbasset Benzertiha, Bartosz Kierończyk, Anna Łukomska, Izabela Wesołowska, Mateusz Rawski
Animals
19.
Insect and fish by-products as sustainable alternatives to conventional animal proteins in animal nutrition
Laura Gasco, Gabriele Acuti, Paolo Bani, Zotte Dalle, Pier Danieli, Angelis De, Riccardo Fortina, Rosaria Marino, Giuliana Parisi, Giovanni Piccolo, Luciano Pinotti, Aldo Prandini, Achille Schiavone, Genciana Terova, Francesca Tulli, Alessandra Roncarati
Italian Journal of Animal Science
Laura Gasco, Gabriele Acuti, Paolo Bani, Zotte Dalle, Pier Danieli, Angelis De, Riccardo Fortina, Rosaria Marino, Giuliana Parisi, Giovanni Piccolo, Luciano Pinotti, Aldo Prandini, Achille Schiavone, Genciana Terova, Francesca Tulli, Alessandra Roncarati
Italian Journal of Animal Science
20.
ПОЛУЧЕНИЕ ВОДОРАСТВОРИМЫХ ПЕПТИДОВ ИЗ БИОМАССЫ ЛИЧИНОК MUSCA DOMESTICA И ИЗУЧЕНИЕ ИХ СВОЙСТВ
Крылова Л.С., Ремизов Е.К., Смирнова К.Ю., Сорокатая Е.И., Древко Я.Б.
Bulletin of KSAU
Крылова Л.С., Ремизов Е.К., Смирнова К.Ю., Сорокатая Е.И., Древко Я.Б.
Bulletin of KSAU
21.
An Enhanced Variant Designed From DLP4 Cationic Peptide Against Staphylococcus aureus CVCC 546
Bing Li, Na Yang, Xiumin Wang, Ya Hao, Ruoyu Mao, Zhanzhan Li, Zhenlong Wang, Da Teng, Jianhua Wang
Frontiers in Microbiology
Bing Li, Na Yang, Xiumin Wang, Ya Hao, Ruoyu Mao, Zhanzhan Li, Zhenlong Wang, Da Teng, Jianhua Wang
Frontiers in Microbiology
22.
Potential of Black Soldier Fly Production for Pacific Small Island Developing States
Matan Shelomi
Animals
Matan Shelomi
Animals
23.
Antioxidant Status and Liver Function of Young Turkeys Receiving a Diet with Full-Fat Insect Meal from Hermetia illucens
Katarzyna Ognik, Krzysztof Kozłowski, Anna Stępniowska, Piotr Listos, Damian Józefiak, Zenon Zduńczyk, Jan Jankowski
Animals
Katarzyna Ognik, Krzysztof Kozłowski, Anna Stępniowska, Piotr Listos, Damian Józefiak, Zenon Zduńczyk, Jan Jankowski
Animals
24.
Locusta migratoria extruded meal in young steers diet: evaluation of growth performance, blood indices and meat traits of Calves Kasakh white-headed breed
Ivan Gorlov, Marina Slozhenkina, Natalia Mosolova, Vladimir Grishin, Aleksandr Mosolov, Elena Bondarkova, Elena Anisimova, Yulia Starodubova, Svetlana Brekhova, Pavel Andreev-Chadaev
Journal of Applied Animal Research
Ivan Gorlov, Marina Slozhenkina, Natalia Mosolova, Vladimir Grishin, Aleksandr Mosolov, Elena Bondarkova, Elena Anisimova, Yulia Starodubova, Svetlana Brekhova, Pavel Andreev-Chadaev
Journal of Applied Animal Research
25.
Bacterial but not fungal challenge up-regulates the transcription of Coleoptericin
genes in Tenebrio molitor
Ho Jang, Ki Park, Bo Kim, Mohammadie Ali, Young Bae, Snigdha Baliarsingh, Yong Lee, Yeon Han, Yong Jo
Entomological Research
Ho Jang, Ki Park, Bo Kim, Mohammadie Ali, Young Bae, Snigdha Baliarsingh, Yong Lee, Yeon Han, Yong Jo
Entomological Research
26.
Biosurfactants Induce Antimicrobial Peptide Production through the Activation of TmSpatzles in Tenebrio molitor
Tariku Edosa, Yong Jo, Maryam Keshavarz, In Kim, Yeon Han
International Journal of Molecular Sciences
Tariku Edosa, Yong Jo, Maryam Keshavarz, In Kim, Yeon Han
International Journal of Molecular Sciences
27.
Growth Performance and Adaptability of European Sea Bass (Dicentrarchus labrax) Gut Microbiota to Alternative Diets Free of Fish Products
David Pérez-Pascual, Jordi Estellé, Gilbert Dutto, Charles Rodde, Jean-François Bernardet, Yann Marchand, Eric Duchaud, Cyrille Przybyla, Jean-Marc Ghigo
Microorganisms
David Pérez-Pascual, Jordi Estellé, Gilbert Dutto, Charles Rodde, Jean-François Bernardet, Yann Marchand, Eric Duchaud, Cyrille Przybyla, Jean-Marc Ghigo
Microorganisms
28.
Antioxidant enzyme regulating and intracellular ROS scavenging capacities of two novel bioactive peptides from white grub larvae (Polyphylla adstpersa) hydrolysate in A549 cells
Asal Khajepour-Zaveh, Ahmad Asoodeh, Hossein Naderi-Manesh
Medicinal Chemistry Research
Asal Khajepour-Zaveh, Ahmad Asoodeh, Hossein Naderi-Manesh
Medicinal Chemistry Research
29.
A bioinformatic study of antimicrobial peptides identified in the Black Soldier Fly (BSF) Hermetia illucens (Diptera: Stratiomyidae)
Antonio Moretta, Rosanna Salvia, Carmen Scieuzo, Somma Di, Heiko Vogel, Pietro Pucci, Alessandro Sgambato, Michael Wolff, Patrizia Falabella
Scientific Reports
Antonio Moretta, Rosanna Salvia, Carmen Scieuzo, Somma Di, Heiko Vogel, Pietro Pucci, Alessandro Sgambato, Michael Wolff, Patrizia Falabella
Scientific Reports
30.
Enhanced Antioxidant and Cytotoxic Potentials of Lipopolysaccharides-Injected Musca domestica Larvae
Islam El-Garawani, Hesham El-Seedi, Shaden Khalifa, Azab El, Marwa Abouhendia, Shaymaa Mahmoud
Pharmaceutics
Islam El-Garawani, Hesham El-Seedi, Shaden Khalifa, Azab El, Marwa Abouhendia, Shaymaa Mahmoud
Pharmaceutics
31.
Gut immunity in European sea bass (Dicentrarchus labrax): a review
S. Picchietti, A. Miccoli, A.M. Fausto
Fish & Shellfish Immunology
S. Picchietti, A. Miccoli, A.M. Fausto
Fish & Shellfish Immunology
32.
Last Call for Replacement of Antimicrobials in Animal Production: Modern Challenges, Opportunities, and Potential Solutions
Aneta Nowakiewicz, Przemysław Zięba, Sebastian Gnat, Łukasz Matuszewski
Antibiotics
Aneta Nowakiewicz, Przemysław Zięba, Sebastian Gnat, Łukasz Matuszewski
Antibiotics
33.
Alternative Protein Sources vs. GM Soybean Meal as Feedstuff for Pigs—Meat Quality and Health-Promoting Indicators
Marcin Sońta, Anna Rekiel, Justyna Więcek, Martyna Batorska, Kamila Puppel
Animals
Marcin Sońta, Anna Rekiel, Justyna Więcek, Martyna Batorska, Kamila Puppel
Animals
34.
Use of black soldier fly and house fly in feed to promote sustainable poultry production
A. Dörper, T. Veldkamp, M. Dicke
Journal of Insects as Food and Feed
A. Dörper, T. Veldkamp, M. Dicke
Journal of Insects as Food and Feed
35.
Beyond the protein concept: health aspects of using edible insects on animals
L. Gasco, A. Józefiak, M. Henry
Journal of Insects as Food and Feed
L. Gasco, A. Józefiak, M. Henry
Journal of Insects as Food and Feed
36.
The effect of dietary full-fat Hermetia illucens larvae meal on gut physiology and growth performance in young turkeys
Jan Jankowski, Krzysztof Kozłowski, Zenon Zduńczyk, Anna Stępniowska, Katarzyna Ognik, Bartosz Kierończyk, Damian Józefiak, Jerzy Juśkiewicz
Animal Feed Science and Technology
Jan Jankowski, Krzysztof Kozłowski, Zenon Zduńczyk, Anna Stępniowska, Katarzyna Ognik, Bartosz Kierończyk, Damian Józefiak, Jerzy Juśkiewicz
Animal Feed Science and Technology
37.
Total replacement of fish meal by enriched‐fatty acid
Hermetia illucens
meal did not substantially affect growth parameters or innate immune status and improved whole body biochemical quality of Nile tilapia juveniles
Pamphile Agbohessou, Syaghalirwa Mandiki, Armel Gougbédji, Rudy Megido, Md. Hossain, Jaeger De, Yvan Larondelle, Frédéric Francis, Philippe Lalèyè, Patrick Kestemont
Aquaculture Nutrition
Pamphile Agbohessou, Syaghalirwa Mandiki, Armel Gougbédji, Rudy Megido, Md. Hossain, Jaeger De, Yvan Larondelle, Frédéric Francis, Philippe Lalèyè, Patrick Kestemont
Aquaculture Nutrition
38.
Feasibility of superworm,
Zophobas morio
, meal as a partial fishmeal replacer in fingerling rainbow trout,
Oncorhynchus mykiss
, diet: growth performance, amino acid profile, proteolytic enzymes activity and pigmentation
Shekarabi Hosseini, Mehrgan Shamsaie, Akbar Banavreh
Aquaculture Nutrition
Shekarabi Hosseini, Mehrgan Shamsaie, Akbar Banavreh
Aquaculture Nutrition
39.
Identification of a novel proline‐rich antimicrobial protein from the hemolymph of
Antheraea mylitta
Trinath Chowdhury, Santi Mandal, Soumita Dutta, Ananta Ghosh
Archives of Insect Biochemistry and Physiology
Trinath Chowdhury, Santi Mandal, Soumita Dutta, Ananta Ghosh
Archives of Insect Biochemistry and Physiology
40.
Antibacterial activity of selected invertebrate species
Salwa Ali, Ruqaiyayh Siddiqui, Kuppusamy Sagathevan, Naveed Khan
Folia Microbiologica
Salwa Ali, Ruqaiyayh Siddiqui, Kuppusamy Sagathevan, Naveed Khan
Folia Microbiologica
41.
Performance, nutrient digestibility and selected gut health parameters of broilers fed with black soldier fly, lesser mealworm and yellow mealworm
der Van, J.V. Nørgaard, R.M. Engberg
Journal of Insects as Food and Feed
der Van, J.V. Nørgaard, R.M. Engberg
Journal of Insects as Food and Feed
Assigning DOI numbers, introducing articles from supplements and recent publications to POL-index database, maintaining anti-plagiarism detection, electronic system to proceed manuscripts and webpage of the Journal with interactive pdf files, and language correction of manuscripts published in Journal of Animal and Feed Sciences are financed in the years 2018–2019 by the Ministry of Science and Higher Education from the funds for science popularization activities, Agreement No. 631/P-DUN/2018.
