0.906
IF5
0.875
IF
Q3
JCR
1.0
CiteScore
0.374
SJR
Q2
SJR
20
MNiSW
165.24
ICV
ORIGINAL PAPER
 
CC-BY 4.0
 
 

Growth hormone gene polymorphism in chicken divergently selected for axial skeleton malformation

B. Wardęcka 1  ,  
K. Jaszczak 1,  
R. Parada 1,  
M. Korczak 1,  
 
1
Department of Molecular Cytogenetics, Institute of Genetics and Animal Breeding, Polish Academy of Sciences, Jastrzębiec, 05-552 Wólka Kosowska, Poland
J. Anim. Feed Sci. 2005;14(3):561–570
Publish date: 2005-08-04
KEYWORDS
ABSTRACT
Chicken growth hormone (cGH), a polypeptyde hormone synthesized in and secreted by pituitary gland, is involved in a variety of physiological functions such as growth, body composition, egg production, aging and reproduction. Two breeds of chickens selected for high and low incidence of scoliosis, were analysed for polymorphisms in the growth hormone gene (GH). The polymorphism of GH gene (PCR-RFLP) was analysed in 30 chickens each breed, Rhode Island Red and Sussex. It was observed five RFLPs in GH gene, three at MspI sites in the intron 1 of cGH gene and two MspI sites in the intron 4 of cGH gene. The selection for axial skeleton malformation appears to have affected the frequency of GH alleles. It was found differences in allelic distribution between the affected (H) and unaffected (L) lines. Whereas none of the alleles was observed as specific to H or L lines for both breeds. The experimental material examined constitutes a valuable source for identification of real genes causing skeletal defects.
CORRESPONDING AUTHOR
B. Wardęcka   
Department of Molecular Cytogenetics, Institute of Genetics and Animal Breeding, Polish Academy of Sciences, Jastrzębiec, 05-552 Wólka Kosowska, Poland
ISSN:1230-1388