ORIGINAL PAPER
Evaluation of methods used in vivo to estimate
the transfer of amino acids and other substrates into
the cells of mammary gland
| 1 | Institute of Physiology, Biochemistry and Nutrition of Farm Animals,
Russian Academy of Agricultural Sciences,
Borovsk-3, Kaluga Region, 249013, Russia |
CORRESPONDING AUTHOR
G. G. Cherepanov
Institute of Physiology, Biochemistry and Nutrition of Farm Animals, Russian Academy of Agricultural Sciences, Borovsk-3, Kaluga Region, 249013, Russia
Institute of Physiology, Biochemistry and Nutrition of Farm Animals, Russian Academy of Agricultural Sciences, Borovsk-3, Kaluga Region, 249013, Russia
Publication date: 2010-05-09
J. Anim. Feed Sci. 2010;19(2):183–194
KEYWORDS
ABSTRACT
In recent years some approaches were developed to estimate the parameters of transport of
amino acids and other substrates into the cell in vivo using arteriovenous concentration difference
and volume blood flow data with their recalculation according to kinetic model of the system:
capillary - interstitium - cell. With the use of literature data and the own results the authors analysed
the present feasibility of this method in the studies of mammary metabolism in productive ruminants
The model estimates were compared with independent measurements (with 13С-amino acids), the
verifying experiments were conducted and some unresolved problems and errors of interpretation
were investigated. The method is recommended to study the adaptive shifts in the activity of amino
acid transport into the mammary secretory cells during milk formation in various nutritional states.
CITATIONS (1):
1.
Fundamental and Applied Scientific Research in the Development of Agriculture in the Far East (AFE-2021)
Makar Zinovy
Makar Zinovy
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