This study evaluated the effects of partially substituting soybean meal (SBM) and maize grain with infertile egg powder (IEP) in broiler diets on carcass characteristics, meat quality, fatty acid, and amino acid (AA) profiles. A total of 196 one-day-old male broilers was randomly assigned to four dietary treatments (7 replicates/treatment, 7 birds/replicate) and reared for 35 days under tropical conditions. The treatments included a 100% basal diet as control (CON), and diets with 4% (IEP4), 6% (IEP6), or 8% (IEP8) IEP replacing part of SBM and maize grain in CON. Results showed that IEP8 increased final body weight, carcass weight, breast meat yield, and abdominal fat mass though the relative percentages of these components remained unchanged. IEP inclusion did not alter carcass quality parameters such as chemical compositions, water holding capacity, cooking loss, or tenderness. However, IEP-fed birds showed elevated breast meat stearic and α-linolenic contents, but reduced oleic acid level compared to CON birds. AA analysis revealed higher threonine, arginine, glycine, alanine, and glutamic acid levels in IEP groups, while phenylalanine, serine, methionine, and isoleucine were lower. In conclusion, substituting up to 8% of maize grain and SBM with IEP can improve broiler growth performance, as well as fatty acid and amino acid profiles in breast meat without compromising its quality. Incorporating infertile egg powder into broiler diets appears to be a promising sustainable alternative protein source in poultry diets.