ORIGINAL PAPER
Evaluation of the possibility of horizontal gene transfer and accumulation of transgenic DNA from the diet in the bodies of rats
 
More details
Hide details
1
Warsaw University of Life Sciences, Faculty of Animal Nutrition and Feed Science, Department of Animal Sciences, Ciszewskiego 8, 02-786 Warsaw, Poland
2
Warsaw University of Life Sciences, Faculty of Horticulture and Landscape Architecture, Department of Plant Genetics, Breeding and Biotechnology, Ciszewskiego 8, 02-786 Warsaw, Poland
CORRESPONDING AUTHOR
I. Kosieradzka   

Warsaw University of Life Sciences, Faculty of Animal Nutrition and Feed Science, Department of Animal Sciences, Ciszewskiego 8, 02-786 Warsaw, Poland
Publication date: 2010-05-09
 
J. Anim. Feed Sci. 2010;19(2):307–315
 
KEYWORDS
ABSTRACT
The procedures for GMO safety tests include traceability of transgenic protein and transgenic DNA if the plant constitutes a component in the diet for an animal. This is due to the possibility of horizontal transfer of genes, accumulation of transgenic DNA in consumer’s organs, or induction of antibiotic resistance in gastrointestinal tract microflora. The last possibility is related to the use of marker genes in the process of transformation. In an in vivo experiment conducted on laboratory rats with the use of transgenic cucumbers expressing the pre-prothaumatin gene, the presence of transgenic DNA in the tissue of kidneys and liver was not detected. Resistance to neomycin of gastrointestinal tract microflora of the rats fed the GMO diet was not found, despite the use of marker genes (npt II) in the process of transformation of the investigated plants.
 
CITATIONS (6):
1.
DNA degradation in genetically modified rice with Cry1Ab by food processing methods: Implications for the quantification of genetically modified organisms
Fuguo Xing, Wei Zhang, Jonathan Nimal Selvaraj, Yang Liu
Food Chemistry
 
2.
Genetically Modified Crops Expressing 35S-Thaumatin II Transgene: Sensory Properties and Food Safety Aspects
Maria Szwacka, Wojciech Burza, Renata Zawirska-Wojtasiak, Michał Gośliński, Aleksandra Twardowska, Janina Gajc-Wolska, Iwona Kosieradzka, Małgorzata Kiełkiewicz
Comprehensive Reviews in Food Science and Food Safety
 
3.
Degradation of Endogenous and Exogenous Genes of Genetically Modified Rice withCry1Abduring Food Processing
Wei Zhang, Fuguo Xing, Jonathan Nimal Selvaraj, Yang Liu
Journal of Food Science
 
4.
Detection of genetically modified food in digesta and organs of rats fed transgenic potato
A. Sattarzadeh, H. Rahnama, M. Nikmard, B. Ghareyazie
Journal of Animal and Feed Sciences
 
5.
Results of a 16-week safety assurance study with rats fed genetically modified Bt maize: effect on growth and health parameters
Beata Szymczyk, Witold Szczurek, Sylwester Świątkiewicz, Krzysztof Kwiatek, Zbigniew Sieradzki, Małgorzata Mazur, Dariusz Bednarek, Michał Reichert
Journal of Veterinary Research
 
6.
Using droplet digital PCR to detect plant DNA in tissues of zebrafish ( Danio rerio ) fed genetically modified maize
Shanshan Dong, Dini Zhang, Cigang Yu, Zhenhua Zhang, Yan Liu
Aquaculture Research
 
ISSN:1230-1388