ORIGINAL PAPER
A note on the distribution of insulin receptor mRNA in tissues of neonatal Holstein calves
,
 
,
 
,
 
,
 
C. Xia 3
,
 
C. Xu 3
 
 
 
More details
Hide details
1
Laboratory of Animal Nutritional and Metabolic Diseases and Toxicopathy, College of Animal Science and Veterinary Medicine, Jilin University, Changchun, Jilin, 130062, P.R. China
 
2
College of Veterinary Medicine, Northeast Agriculture University, Harbin, Heilongjiang, 150030, P.R. China
 
3
College of Animal Science and Technology, Heilongjiang August First Land Reclamation University, Daqing, Heilongjiang, 163319, P.R. China
 
 
Publication date: 2009-11-06
 
 
Corresponding author
Z. Wang   

Laboratory of Animal Nutritional and Metabolic Diseases and Toxicopathy, College of Animal Science and Veterinary Medicine, Jilin University, Changchun, Jilin, 130062, P.R. China
 
 
J. Anim. Feed Sci. 2009;18(4):613-619
 
KEYWORDS
ABSTRACT
Characterization of the distribution of insulin receptor (InsR) mRNA in tissues is crucial to understand insulin physiology in dairy cattle. The expression of the InsR gene in various tissues of three male neonatal Holstein calves was analysed using reverse transcription polymerase chain reaction. The results showed that the InsR mRNA was detectable in the liver, subcutaneous adipose, Semitendinosus muscle, pancreas, kidney cortex, spleen, heart, lung, mesenteric lymph node, aorta, duodenum, colon, hypothalamus, pituitary, cerebral cortex and cerebellar cortex. Expression of InsR mRNA was particularly higher (P<0.05) in the liver, Semitendinosus muscle, pancreas, aorta, hypothalamus and pituitary tissue than other tissues detected. The broad tissue expression of the InsR gene indicates that the InsR has important physiological functions in multiple tissues in neonatal Holstein calves.
 
CITATIONS (1):
1.
High Insulin Concentrations Repress Insulin Receptor Gene Expression in Calf Hepatocytes Cultured in Vitro
Zhigang Zhang, Xiaobing Li, Guowen Liu, Li Gao, Changming Guo, Tao Kong, Hongbin Wang, Ruifeng Gao, Zhe Wang, Xinglin Zhu
Cellular Physiology and Biochemistry
 
ISSN:1230-1388
Journals System - logo
Scroll to top