TY - JOUR JO - Journal of Animal and Feed Sciences J2 - J. Anim. Feed Sci. SN - 1230-1388 VL - 15 IS - 4 PY - 2006 ID - Sobeková2006 TI - Effects of feed supplemented with selenite or Se-yeast on antioxidant enzyme activities in lamb tissues AB - The activities of antioxidant enzymes: superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GSHPx), glutathione-S-transferase (GST) and glutathione reductase (GR) were examined in liver, kidney cortex and heart tissues of lambs fed diets supplemented with inorganic (sodium selenite) and an organic (Se-yeast) form of selenium. Additional selenium resulted in a significant increase of the Se content in the examined tissues in both supplemented groups. The activities of GSHPx, CAT in the liver as well as of CAT, GST and SOD in the kidney cortex were significantly lower in the Se-yeast supplemented group when compared with both the control and selenite-fed groups. In the heart, the activities of all of the assayed enzymes increased in both supplemented groups. SOD activity was found to be significantly higher in the Se-yeast supplemented group when compared with the selenite group. In addition, two Cu, Zn-SOD isoenzymes of higher band intensity were generated in this group, probably as a result of oxidative stress, which was also manifested by a significant increase of thiobarbituric acid reactive substances (TBARS). The presented results suggest specific regulation of antioxidant enzyme activities in the tissues of lambs depending on the form of selenium intake. AU - Sobeková, A. AU - Holovská, K. AU - Lenártová, V. AU - Holovská Jr., K. AU - Javorský, P. AU - Boldižárová, K. AU - Grešáková, Ľ. AU - Leng, Ľ. SP - 569 EP - 577 DA - 2006 DO - 10.22358/jafs/66926/2006 UR - https://doi.org/10.22358/jafs/66926/2006 ER -