%0 Journal Article %9 journal article %J Journal of Animal and Feed Sciences %@ 1230-1388 %V 29 %N 1 %D 2020 %F Ibrahim2020 %T In-ovo and dietary supplementation of selenium nano-particles influence physiological responses, immunological status and performance of broiler chicks %X This study aimed to explore impacts of in ovo injection and dietary supplementation of selenium nanoparticles (SeNPs) on physiological responses, immunological status and performance of broiler chicks. A total of 210 broiler eggs were divided into 3 in ovo groups: not in ovo injected and in ovo injected with 5 or 10 ppb SeNPs. The hatched chicks from each in ovo group were divided into 2 dietary groups, with or without 10 ppb SeNPs/kg ration for 5 weeks. Live body weight and body weight gain were significantly increased in all SeNPs injected or supplemented groups. Feed conversion ratio for the whole feeding period was improved by SeNPs feed supplementation. Serum triglycerides and malondialdehyde contents were significantly decreased, while high-density lipoprotein cholesterol, immunoglobulin status, reduced glutathione content and glutathione reductase activity were increased by both examined routes of SeNPs delivery. It can be concluded that SeNPs in ovo injection with a dose up to 10 ppb/egg along with SeNPs diet supplementation at a dose of 10 ppb/kg had a positive effect on performance and physiological, antioxidant and immunological status of broiler chicks. %A Ibrahim, N.S. %A Sabic, E.M. %A Wakwak, M.M. %A El-Wardany, I.E. %A El-Homosany, Y.M. %A El-Deen Mohammad, N. %P 46-58 %R 10.22358/jafs/118209/2020 %U https://doi.org/10.22358/jafs/118209/2020