0.857
IF5
0.900
IF
Q3
JCR
0.92
CiteScore
0.405
SJR
Q2
SJR
20
MNiSW
165.24
ICV
SHORT COMMUNICATION
 
CC-BY 4.0
 
 

Urea transporter mRNA in papilla and pelvic epithelium of kidney in normal and low protein fed sheep

J.-M. Elalouf 2,  
R. Boivin 3,  
A. Cirio 4  
 
1
Departamento Básico de Medicina, Facultad de Medicina, 11800 Montevideo, Uruguay
2
Service de Biochimie et de Génétique Moléculaire, CEA /Saclay, 91191 Gif-Sur-Yvette, France
3
UMR Laboratoire de Physiologie, Ecole Vétérinaire de Lyon, 69280 Marcy L’Etoile, France
4
Departamento de Fisiología, Facultad de Veterinaria, 11600 Montevideo, Uruguay
J. Anim. Feed Sci. 2004;13(Suppl. 1):365–368
Publish date: 2004-08-30
KEYWORDS
ABSTRACT
An urea transporter (UT) cDNA fragment, sharing high identity with rabbit, rat and human UTA2, was cloned by RT-PCR from papilla and upper pelvic epithelium of sheep kidney. Quantitative RT-PCR after low protein diets disclosed, compared to normal protein fed sheep, a significant reduction in UT mRNA levels in pelvic epithelium (852±172 vs 2024±260 molecules; P<0.01) and a tendency to its increase in papilla (7959±1741 vs 5447±1040 molecules; NS). The reduction of UT expression in the upper pelvic epithelium could be relevant for the renal urea conservation in protein-restricted sheep.
CORRESPONDING AUTHOR
A. Cirio   
Departamento de Fisiología, Facultad de Veterinaria, 11600 Montevideo, Uruguay
ISSN:1230-1388