SHORT COMMUNICATION
The isopropyl ester of methionine hydroxy-analogue is absorbed through the rumen wall in the cow
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1
CERN, ADISSEO France SAS, 03100 Commentry, France
 
2
Research and Development Department, ADISSEO France SAS, 92160 Antony, France
 
 
Publication date: 2004-08-30
 
 
Corresponding author
J. C. Robert   

Research and Development Department, ADISSEO France SAS, 92160 Antony, France
 
 
J. Anim. Feed Sci. 2004;13(Suppl. 1):269-272
 
KEYWORDS
ABSTRACT
A new form of methionine, the isopropyl ester of methionine hydroxy analog (HMBi), has been proven to be available for milk protein synthesis in dairy cows. Studies have also shown that HMBi can be degraded by rumen micro-organisms. By two different experimental approaches (emptied and washed rumen; catheterization of the ruminal vein), we have demonstrated that HMBi ability to be rapidly absorbed by the rumen wall can explain its partial protection from microbial degradations. The high efficiency of HMBi to pass through biological membranes seems to be due to the molecule’s isopropyl ester radical.
 
CITATIONS (5):
1.
Effects of 2-hydroxy-4-(methylthio) butanoic acid isopropyl ester on growth and blood components in growing Holstein steers
Zhaoyu Han, Baokui Yang, Zhen Yang, Yumeng Xi
Animal Science Journal
 
2.
Methionine Availability in Plasma of Dairy Cows Supplemented with Methionine Hydroxy Analog Isopropyl Ester
B. Graulet, C. Richard, J.C. Robert
Journal of Dairy Science
 
3.
Effects of 2-hydroxy-4(methylthio) butanoic acid isopropyl ester on rumen fermentation in cashmere goats
Yali Feng, Yuyan Cong, Hongwei Deng, Dongxin Guo, Haiying Liu
Revista Brasileira de Zootecnia
 
4.
Effect of inclusion of HMBi in the ration of goats on feed intake, nutrient digestibility, rumen bacteria community and blood serum parameters
Dong Chen, Jingcai Yan, Weijun Shen, Yang Song, Xinyi Lan, Kangle Yi, Aziz Muhammad
Journal of Animal Physiology and Animal Nutrition
 
5.
Effects of a rumen-protected form of methionine and a methionine analogue on the lactation performance of dairy cows
J. Čermáková, V. Kudrna, J. Illek, K. Blažková, J. Haman
Czech Journal of Animal Science
 
ISSN:1230-1388
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