ORIGINAL PAPER
Effects of spermine supplementation on blood biochemical parameters, amino acid profile and ileum expression of amino acid transporters in piglets
1
Sichuan Agricultural University, Institute of Animal Nutrition, Chengdu 611130, Sichuan, China
2
Key Laboratory for Animal Disease-Resistance Nutrition of China Ministry of Education, Chengdu 611130, Sichuan, China
3
Sichuan Agricultural University, Maize Research Institute, Chengdu 611130, Sichuan, China
Publication date: 2019-12-27
Corresponding author
G. Liu
Sichuan Agricultural University, Institute of Animal Nutrition, Chengdu 611130, Sichuan, China; Key Laboratory for Animal Disease-Resistance Nutrition of China Ministry of Education, Chengdu 611130, Sichuan, China
Sichuan Agricultural University, Institute of Animal Nutrition, Chengdu 611130, Sichuan, China; Key Laboratory for Animal Disease-Resistance Nutrition of China Ministry of Education, Chengdu 611130, Sichuan, China
J. Anim. Feed Sci. 2019;28(4):337-345
KEYWORDS
TOPICS
ABSTRACT
The effects of spermine supplementation and extended spermine
supplementation on blood biochemical parameters, serum amino acid profile
and ileum expression of amino acid transporters in piglets were examined
in this study. Piglets were fed adequate nutrient intake supplemented or not
with spermine (0.4 mmol/kg body weight) for 7 h or 3, 6 or 9 days. Spermine
supplementation significantly increased aspartate aminotransferase activity and
albumin content, but decreased triglyceride level in serum (P < 0.05). There was
a significant increase in levels of arginine, histidine, isoleucine, leucine, threonine,
valine, alanine, asparagine, serine, proline, taurine and tyrosine (P < 0.05) in
the spermine-treated groups. Spermine significantly increased the mRNA levels
of SLC1A1, SLC1A5, SLC7A1, SLC7A7, SLC7A9, SLC5A1, SLC6A19 and
SLC15A1 in ileum (P < 0.05). The extended spermine supplementation exerted
different effects on the blood biochemical parameters, amino acid profile and
ileum expression of amino acid transporters in comparison to the 7-h group
(P < 0.05). In summary, spermine supplementation can affect biochemical
parameters and amino acid profile in serum and may enhance the ileum
absorption of amino acids by increasing the expression of amino acid
transporters in piglets.
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CITATIONS (1):
1.
Serum biochemical parameters and amino acids metabolism are altered in piglets by early-weaning and proline and putrescine supplementations
Jing Wang, Yuxin Xiao, Jianjun Li, Ming Qi, Bie Tan
Animal Nutrition
Jing Wang, Yuxin Xiao, Jianjun Li, Ming Qi, Bie Tan
Animal Nutrition
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