0.906
IF5
0.875
IF
Q3
JCR
1.0
CiteScore
0.374
SJR
Q2
SJR
20
MNiSW
165.24
ICV
ORIGINAL PAPER
 
CC-BY 4.0
 
 

Effects of spermine supplementation on blood biochemical parameters, amino acid profile and ileum expression of amino acid transporters in piglets

T. Fang 1, 2,  
G. Jia 1, 2,  
H. Zhao 1, 2,  
X. Chen 1, 2,  
C. Wu 1, 2,  
B. Xue 1, 2,  
J. Cai 1, 2,  
G. Tian 1, 2,  
J. Wang 3,  
G. Liu 1, 2  
 
1
Sichuan Agricultural University, Institute of Animal Nutrition, Chengdu 611130, Sichuan, China
2
Key Laboratory for Animal Disease-Resistance Nutrition of China Ministry of Education, Chengdu 611130, Sichuan, China
3
Sichuan Agricultural University, Maize Research Institute, Chengdu 611130, Sichuan, China
J. Anim. Feed Sci. 2019;28(4):337–345
Publication date: 2019-12-27
KEYWORDS
TOPICS
ABSTRACT
The effects of spermine supplementation and extended spermine supplementation on blood biochemical parameters, serum amino acid profile and ileum expression of amino acid transporters in piglets were examined in this study. Piglets were fed adequate nutrient intake supplemented or not with spermine (0.4 mmol/kg body weight) for 7 h or 3, 6 or 9 days. Spermine supplementation significantly increased aspartate aminotransferase activity and albumin content, but decreased triglyceride level in serum (P < 0.05). There was a significant increase in levels of arginine, histidine, isoleucine, leucine, threonine, valine, alanine, asparagine, serine, proline, taurine and tyrosine (P < 0.05) in the spermine-treated groups. Spermine significantly increased the mRNA levels of SLC1A1, SLC1A5, SLC7A1, SLC7A7, SLC7A9, SLC5A1, SLC6A19 and SLC15A1 in ileum (P < 0.05). The extended spermine supplementation exerted different effects on the blood biochemical parameters, amino acid profile and ileum expression of amino acid transporters in comparison to the 7-h group (P < 0.05). In summary, spermine supplementation can affect biochemical parameters and amino acid profile in serum and may enhance the ileum absorption of amino acids by increasing the expression of amino acid transporters in piglets.
CORRESPONDING AUTHOR
G. Liu   
Sichuan Agricultural University, Institute of Animal Nutrition, Chengdu 611130, Sichuan, China; Key Laboratory for Animal Disease-Resistance Nutrition of China Ministry of Education, Chengdu 611130, Sichuan, China
 
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ISSN:1230-1388