Effect of intravenous administration of glucagon-like peptide 1 on growth hormone secretion in sheep

We examined effects of intravenous administration of glucagon-like peptide 1 (GLP-1) on growth hormone (GH) secretion in ruminants. Four Suffolk rams, aged 2 years, were fed at 16.00 h. They were bled every 5 min from 12.00 until 17.00 h. GLP-1(7-36)amide was intravenously infused at a rate of 1.2 pmol/kg/min from 12.00 to 17.00 h. GH peak frequency was significantly (P<0.05) increased. GLP-1 did not affect GH peak amplitude. Plasma insulin levels transiently increased just after the start of GLP-1 infusion. Plasma glucose levels did not change. GLP-1 may be a physiological regulator of spontaneous pulsatile GH secretion in ruminants.

Submit your paper

Instructions for Authors

Archive

Send by email

Regulation of Nod-like receptor expression in the liver of ewes during early pregnancy

The role of sheep’s milk bioactive substances in the prevention of metabolic and viral diseases

Changes in nuclear factor kappa B components expression in the ovine spleen during early pregnancy

Brain-derived neurotrophic factor (BDNF) affects somatotrophic axis activity in sheep

Changes in the content and intensity of oxidation of lipid compounds in the kidneys of lambs fed diets with rapeseed and fish oils – effect of antioxidant supplementation

Indexes

Keywords index

Topics index

Authors index

ISSN:

1230-1388

Assigning DOI numbers, introducing articles from supplements and recent publications to POL-index database, maintaining anti-plagiarism detection, electronic system to proceed manuscripts and webpage of the Journal with interactive pdf files, and language correction of manuscripts published in Journal of Animal and Feed Sciences are financed in the years 2018–2019 by the Ministry of Science and Higher Education from the funds for science popularization activities, Agreement No. 631/P-DUN/2018.